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Priority-setting regarding offshore substances and preparations

Appendix 2 Data collection

The environmental pre-screening is primarily based on information provided by the chemical suppliers and entered into the PROSPECT database. In addition to this information, relevant data has been obtained from the following data sources:

Ecotoxicity:

Relevant databases and handbooks specified in the Nordic data collection strategy (Nordic Council of Ministers TemaNord 1994:589)
Danish Ministry of Environment and Energy: Statutory Order 921/ 1996 on Quality objectives for the aquatic environment and demands to discharge of certain dangerous substances to rivers, lakes and the sea.
Other compilations of water quality criteria (e.g. from the Netherlands, US-EPA, Canada, new Danish proposals)
EU list of dangerous substances (Annex I of Directive 67/548/EEC)
Different EU working lists containing "proposals" for environmental hazard classification of chemicals (e.g. reports or working documents from Nordic Council of Ministers, TemaNord 1994:643, bkh Consulting Engineers - substances in group 1 to 8, UBA)

If enough data on ecotoxicological properties cannot be obtained from the above data sources, they may be estimated by using one or more of the quantitative structure-activity relationship (QSAR) programs:

ECOSAR for estimating toxicity to aquatic organisms
BIODEG Probability Program for estimating biodegradability
LOGKOW for estimating the octanol-water partition coefficient

Human health:

EU list of dangerous substances (Annex I of Directive 67/548/EEC)
IARC: Monographs on the evaluation of carcinogenic risks to humans (60 volumes)
Johnsen H. et al.: Occupational neurotoxicity: Criteria document for evaluation of existing data. Copenhagen, 1992
Hass U. et al.: Reproduktionsskadende stoffer i arbejdsmiljøet. AMI-rapport nr. 35, Copenhagen, 1990
EU: International Chemical Safety Cards. Compiler's Guide. International Programme on Chemical Safety. Commission of the European Communities. 1990
PARCOM lists
Flyvholm, M.: Allergirapporter fra AMI

If the information on human toxicology obtained from these data sources does not yield satisfactory results, additional information may be obtained from the following books and databases:

General Handbooks

Special Handbooks

Databases

RTECS

Merck

Sax

Patty's Industrial Hygiene

Gosselin

Kühn-Birett

Hommel

MAK-Kommision

ACGIH

ECETOX

DOSAGE

Martindale

Irritation/allergy:

Grant

Cronin

Fischer

Fousseraud

Nervous system:

Ethel Browning

Arlien-Søborg

Reproduction:

Shepard

Schradein

Norpoth & Waschinsky

Barlov & Sullivan

General databases:

RTECS

HSDB

ECDIN

Toxicology:

TOXLINE

TOXLIT

Medicine:

MEDLINE

EMBASE

Cancer:

Cancerlit

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