Environmental Assessment of Veterinary Medicinal Products in Denmark

11. Appendix C. Quantification of the use of single substances.

Tabel C 1
Forbruget af lægemiddelstoffer (tons aktivt stof i) 1996 og 1997, anvendt terapeutisk til fordøjelse og metabolisme sygdomme (gruppe QA).

Table C 1
Consumption (tons active substance) in 1996 and 1997 used therapeutically for the alimentary tract and metabolism (gruop QA).

 

1996

1997

 

1996

1997

Substance

Tons

Tons

Substance

Tons

Tons

Neomycinsulfat

3.366

3.926

Benzetimidchlorid

<0.001

-

(antibiotic)

-

-

-

-

-

Colistinsulfat

0.208

0.193

Boric acid

1.879

1.593

Alfa-tocopherolacetat

0.106

0.077

Calciumglyconat

7.629

7.748

Menbuton

0.073

0.062

Magnesiumhypophosphit

0.858

1.054

Dihydrostreptomycin

0.091

0.089

Selen

<0.001

<0.001

(antibiotic)

-

 

Total

14.212

14.743


Tabel C 2
Forbruget af lægemiddelstoffer (kg aktiv stof) til hormon behandling i 1996 og 1997 (gruppe QH og QG). * Antibiotika givet sammen med hormoner.

Table C 2
Consumption (kg active substance) in 1996 and 1997 of hormones (gruop QH and QG).

-

1996

1997

 

1996

1997

Substance

kg

kg

Substance

kg

kg

Oxytocin

0.085

0.103

Choriongonadotropin

0.022

0.030

prednisolonacetat (methyl)

8.333

10.728

Serumgonadotropin

0.056

0.102

Gonadorelin

0.001

<0.001

Proligeston

1.160

0.848

Dexamethasoniconitat

2.035

1.965

Luprostiol

0.330

0.356

Flumetason

0.056

0.041

Cloprostenolnatrium

0.040

0.040

Vasopressin

0.003

-

Total Hormones

27.301

28.673

Buserelinacetat

<0.001

<0.001

Oxytetracyklin*

13.020

14.150

Medroxyprogesteronacatat

14.916

14.149

Sulfadimidin*

1156.0

1267.8

Dinoprost

0.303

0.349

Benzylpenicillin*

43.665

38.692

-

-

-

Streptocillin*

145.55

128.98

* Antibiotics in connection with hormones.


Tabel C 3.

Forbruget af antibiotika (tons aktiv stof) anvendt terapeutisk i 1996 og 1997 (gruppe QJ01 og QJ51).

Table C 3.
Consumption (tons active substance) in 1996 and 1997 of antibiotics for therapeutical treatment (gruop QJ01+QJ51).

 

1996

1997

 

1996

1997

Substance

Tons

Tons

Substance

Tons

Tons

Sulfadiazin

3.414

4.476

Sulfapyrazol

0.969

0.397

Dihydrostreptomycin

2.557

2.806

Metronidazol

0.014

0.015

Tetracyclin/Chlortetracyklin

9.869

11.090

Baquiloprim

0.010

0.007

Benzylpenicillin

6.321

7.336

Cloxacillinnatrium

0.067

0.084

Spiramycin

0.543

0.621

Bacitracin

0.021

0.012

Penethamathydroiodid

0.637

0.686

Neomycin

0.063

0.063

Tiamulinhydrogenfumarat

2.573

2.948

Enrofloxacin

0.391

0.442

Gentamicinsulfat

0.003

0.003

Trimethoprim

0.963

1.204

Spectionomycin

0.845

0.853

Ampicillin

1.075

0.603

Sulfadimidin

0.074

0.060

Oxilinc acid

0.778

0.726

Oxytetracyklin

2.600

2.662

Doxycyklin

0.009

0.009

Amoxicillin

3.874

6.281

Danofloxacin

<0.001

0.004

Florfenicol

0.039

0.047

Cefadroxil

0.001

0.036

Tylosin

1.380

1.084

Ceftiofur

0.022

0.033

Lincomycin

2.570

2.323

Cefquinom

<0.001

<0.001

Clinadamycin

0.018

0.019

Cefaperazon

-

0.002

Sulfatroxazol

0.457

0.563

Total

42.968

48.530

Sulfadoxin

0.809

1.034

 

 

 


Tabel C 4.
Forbruget af anæstetika (tons aktiv stof) i 1996 og 1997.

Table C 4.
Consumption (tons active substance) in 1996 and 1997 of Central Nervous System (CNS) active substances.

 

1996

1997

 

1996

1997

Substance

Tons

Tons

Substance

Tons

Tons

Medetomidinhydrochlorid

<0.001

<0.001

Amperozid

<0.001

<0.001

Xylasin

0.006

0.006

Diprenorphin

<0.001

<0.001

Propofol

<0.001

0.002

Etorphin

<0.001

<0.001

Ketaminhydrochlorid

0.004

0.004

Acepromazinmelat

<0.001

<0.001

Detomidinhydrochlorid

<0.001

<0.001

Tiletaminhydrochlorid

<0.001

<0.001

Azeperon

0.002

-

Butanilicainphosphat

0.027

0.031

Metamizolnatrium

0.198

0.177

Romifidin

-

<0.001

Propionnyl-
promazinphosphat

<0.001

<0.001

Zolazepam

<0.001

<0.001

 

 

 

Total

0.237

0.230


Tabel C 5

Forbruget af antiparasit midler (tons aktiv stof) (A eller B udlevering) i 1996 og 1997(gruppe QP).

Table C 5
Consumption of antiparacetic agents (tons active substance) in 1996 and 1997(A or B labelled substances) (gruop QP).

 

1996

1997

Substance

Tons

Tons

Sulfaclozinnatrium

0.242

0.236

Total A and B labelled

0.242

0.236


Tabel C 6

Forbruget af antibiotika (tons aktiv stof) som antimicrobielle vækst fremmere i Danmark i perioden 1989-97 samt første halvår af 1998. Kilde: Plantedirektoratet.

Table C 6
Consumption of Antibiotics (tons active substance) used as Antimicrobial Growth Promoters in Denmark 1989-97 and for the first six months of 1998. Source: The Danish Plant Directorate.

Look here!


Tabel C 7.

Forbruget af Coccidiostatika (tons aktiv stof) i Danmark i 1989-1997 samt de første 6 måneder af 1998. Kilde: Platedirektoratet.

Table C 7.
Consumption of Coccidiostatics (tons active substance) in Denmark in 1989-1997 and first six months of 1998. Source: The Danish Plant Directorate

Look here!


Tabel C 8.

Opgørelse over forbruget af forderlægemidler (kg aktiv stof) i Danmark i 1995 og 1996. Kilde: Plantedirektoratet.

Table C 8.
Consumption of Feed Administrated Drugs ( kg active substance) used in poultry. fish farms and livestock. Data from 1995 and 1996. Source: The Danish Plant Directorate.

 

1995

1996

Medicin in feed additive (foderlægemidler) (kg active substance)

-

-

Antibiotics

-

-

Sulfadiazin/trimetroprim

1489

1013.8

Oxilinc acid

906

510.8

Eurofloxacin

17.0

0

Tiamutin

22.0

45.3

Lincomycin

1.5

3.73

Tylosin

1.9

0.6

Chlortetracycline

34.0

131.9

Trimazin

1.8

0

Substances against worms

-

-

Flubendazol. Flubenol

6.9

7.0

Thiophanat. Nemefax

11.0

7.4

Ivomectin

0

0.18

Total

2.491.1

1720.7


Tabel C 9

Forbruget af antimicrobielle vækstfremmer (tons aktiv stof) i 1995 for forskellige dyre typer. Kilde: Plantedirektoratet. Fordeling på dyrearter er baseret på skøn.

Table C 9.
Consumption of antimicrobial growth promoters (tons active substance) during 1995 distributed on differet animal species, Source: The Danish Plant Directorate. Distribution amoung animal species is estimated.

Antimicrobial growth promoter

Total
Tons

Pigs
Tons

Cattle
Tons

Poultry
Tons

Flavomycin

0.048

-

-

0.048

Avoparcin

5.690

2.500

2.090

1.100

Monensin natrium

5.007

-

5.007

(2.463)*

Salinomycin

0.850

0.850

-

(3.758)*

Spiramycin

0.507

-

-

0.507

Tylosin

52.275

52.275

-

-

Avilamycin

1.665

0.265

-

1.400

Zinkbacitracin**

7.910

6.000

-

0.610

Carbadox

1.181

1.181

-

-

Olaquindox

16.213

16.213

-

-

Virginamycin

2.590

1.500

-

-

* Used as coccidiostatics.
** Approximately 1.3 Tons used in mink.


Table C 10
Calculation example showing how the data recveied from the Dansh Medical Agency was translated from packet numbers in to weight of active compound

Tiamulinhydrogenfumerat

ATC code

Number in recived data list

Official Number in Agency list

Number of packets sold in 1996

Amount of active substance in gram in packet size

Total amount of

compound in gram

QJ01XX92

35

´036525

129

400

51600

premix

 

36

´036533

1713

500

856500

premix

226

´426759

120

2000

240000

 

247

´442970

59

500

29500

 

248

´453456

7

600

4200

 

319

´529453

2626

31.25

82062.5

 

320

´529461

3070

312.5

959375

 

 

 

 

SUM

2223238

gram

 

2.22 tons