Report on the Health Effects of Selected Pesticide Coformulants
Table 3: Summary table of critical effects and current regulation on selected coformulants
(Tabel 3: Oversigtstabel over kritiske effekter og gældende regulering af udvalgte hjælpestoffer)
Chemical name
Acronym
Critical effects
EU-
classificationa,1)
OEL DK2)
C-value3)
Manganese (II) sulphate
Manganese (II) sulphide
Neurological effects:
LOAEC humans 0.14-1.59
mg Mn/m3 as total dust
Xn; R48/20/22
N; R51/53
-
0.2 mg
Mn/m3
(inorganic
compounds)
0.001 mg
Mn/m3
(inorganic
dust)
Diammonium sulphate
Lung: LOAEC rat 0.5-1
mg/m3
-
-
-
Dimethyl ether
DME
Acute: CNS depression
humans
RDT: Liver NOEC rat 380
mg/m3
Fx; R12
1000 ppm
(1885
mg/m3)
1 mg/m3
Hexamethylenetetramine
Sensitisation inhalation,
skin contact
F; R11 R42/43
-
-
1-Methyl-1,2-ethanediyl dioleate
No data available
-
-
-
Isopropyl myristate
Irritation skin, respiratory
tract
-
-
-
Sodium ligninsulphonate
Irritation eye, skin,
respiratory tract
-
-
-
Calciumdodecylbenzene-
sulphonate
CaDBS
Possibly irritation eye,
skin, respiratory tract - by
analogy with LAS
-
-
-
Ethylene glycol
EG
Kidney: NOAEL rat 200
mg/kg b.w./day
Developmental effects:
NOAEC mouse 1000
mg/m3
Irritation respiratory tract:
LOAEC human 17 mg/m3
Xn; R22
10 ppm
(26 mg/m3)
-
Propylene glycol
PG
Skin and mucous
membrane
irritation/dehydration
-
-
-
2-Butoxyethanol
EGBE
Haemolysis: NOEC
human above 3 mg/m3
Irritation eye, skin
Irritation respiratory tract:
NOAEC human above 100
mg/m3
Xn; R20/21/22
Xi; R36/38
20 ppm
(98 mg/m3)
0.04 mg/m3 L
1-Methoxy-2-propanol
2PG1ME
Irritation eye, mucous
membranes, respiratory
tract
-
50 ppm
(300 mg/m3)
skin notation
1 mg/m3
Diethylene glycol mono-n-butyl
ether
DEGBE
Irritation skin, eye
RDT: skin irritation
NOAEL 100-200 rat
mg/kg b.w./day
Xi; R36
100 mg/m3
0.02 mg/m3 L
Dipropylene glycol monomethyl
ether
DPGME
Eye and mucous
membrane irritation
-
50 ppm
(300 mg/m3)
skin notation
1 mg/m3
Polyethyleneglycol dodecylether
polyEGDE
Skin and eye irritation
-
-
-
Chemical name
Acronym
Critical effects
EU-
classificationa,1)
OEL DK2)
C-value3)
Cyclohexanone
CNS depression: LOAEC
human 162 mg/m3
Irritation skin, eye,
respiratory tract
R10 Xn; R20
10 ppm
(40 mg/m3)
skin notation
0.1 mg/m3
1-Methyl-2-pyrrolidone
NMP
Irritation eye, skin,
respiratory tract
Xi; R36/38
5 ppm
(20 mg/m3)
0.5 mg/m3
4-Hydroxy-4-methyl-2 pentanone
HMP
Irritation eye, mucous
membranes
Xi, R36
50 ppm
(240 mg/m3)
0.1 mg/m3
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