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Blågrønalgetoksiner i bade- og drikkevand

Litteraturliste

Abdel-Rahman S., El-Ayouty Y.M. & Kamael H.A. (1993): Characterization of heptapeptide toxins extracted from Microcystis aeruginosa (Egyptian isolate). Comparison with some synthesized analogs. Int. J. Peptide Protein Res. 41: 1-7

Adelman W.J.Jr., Fohlmeister J.F., Sasner J.J.Jr. & Ikawa M. (1982): Sodium channels blocked by aphantoxin obtained from the blue-green alga Aphanizomenon flosaquae. Toxicon 20: 513-516.

Alfonso A., Louzao M.C., Vieytes M.R. & Botana L.M. (1994): Comparative study of the stability of saxitoxin and neosaxitoxin in acidic solutions and lyophilized samples. Toxicon. Vol. 32, No. 12: 1593-1598.

Al-Layl K.J., Beattie K.A., Poon G.K., Fawell J.K. & Codd G.A. (1992): Cyanobacterial toxins: Recovery of peptide and alkaloid toxins of Anabaena flosaquae from the tissues of the swan mussel Anodonta cygnea. Proceedings of the Third Nordic Symposium on Toxinproducing Algae, Oslo - 1988. NIVA.

Al-Layl K.J., Poon G.K. & Codd G.A. (1988): Isolation and purification of peptide and alkaloid toxins from Anabaena flosaquae using high-performance thin-layer chromatography. Journal of Microbial Methods 7: 251-258.

An J. & Carmichael W.W. (1994): Use of a colorimetric protein phosphatase inhibition assay and enzyme linked immunosorbent assay for the study of microcystins and nodularins. Toxicon 32: 1495-1507.

Annadotter H. (1993): Algtoxiner i dricksvatten en undersökning vid två svenska vattenverk samt en litteraturstudie. VA-Forsk, rapport nr. 1993-03. Svenska vatten- och avloppsverksföreningen, VAV, Stockholm, 106 pp.

AOAC (Official Methods of Analysis) (1984): Paralytic shellfish poison. Biological Method, 18.086 - 18.092, pp. 344-345.

Aune T. & Berg K. (1986): Use of freshly prepared rat hepatocytes to study toxicity of blooms of the blue-green algae Microcystis aeruginosa and Oscillatoria agardhii. Journal of Toxicogogy and Environmental Health 19: 325-336.

Azevedo S.M.O.F., Wvans W.R., Carmichael W.W. & Namikoshi M. (1994): First report of microcystins from a Brazilian isolate of the cyanobacterium Microcystis aeruginosa. J. App. Phycol. 6: 261-265

Berg K., Carmichael W.W., Skulberg O.M., Benestad C. & Underdal B. (1987a): Investigations of a toxic waterbloom of Microcystis aeruginosa (cyanophyceae) in Lake Akersvatn, Norway. Hydrobiologia 144: 97-103.

Berg K., Skulberg O.M. & Skulberg R. (1987b): Effects of decaying toxic blue-green algae on water quality - a laboratory study. Arch. Hydrobiol. 108: 549-563.

Berg K., Skulberg O.M., Skulberg R., Underdal B. & Willén T. (1986): Observations of toxic blue-green algae (cyanobacteria) in some Scandinavian lakes. Acta Vet. Scand. 27: 440-452.

Bhattacharya R., Lakshmana P.V., Bhaskar A.S.B., Pant S.C. & Dube S.N. (1996): Liver slice culture for assessing hepatotoxicity of freshwater cyanobacteria. Human & Experimental Toxicology 15: 105-110.

Billings W.H. (1981): Water-associated human illness in northeast Pennsylvania and its suspected association with blue-green algae blooms. - I: Carmichael W.W. (Ed.): The water environment. Algal toxins and health. Plenum Press, New York and London, pp. 243-255.

Bishop C.T., Anet E.F.L.J. & Gorham P.R. (1959): Isolation and identification of the fast death factor in Microcystis aeruginosa NRC-1. Can. J. Biochem. Physiol. 37: 453-471.

Bjergskov T., Larsen J., Moestrup Ø., Sørensen H.M. & Krogh P. (1990): Toksiske og potentielt toksiske alger i danske farvande. Fiskeriministeriet, København.

Boland M.P., Smillie M.A., Chen D.Z.X. & Holmes C.F.B. (1993): A unified bioscreen for the detection of diarrhetic shellfish toxins and microcystins in marine and fresh water environments. Toxicon 31 (11): 1393-1405.

Botes D.P., Kruger H. & Viljoen C.C. (1982): Isolation and characterization of four toxins from the blue-green alga, Microcystis aeruginosa. Toxicon 20 (6): 945-954.

Botes D.P., Tuinman A.A., Wessels P.L., Viljoen C.C., Kruger H., Williams D.H., Santikarn S., Smith R.J. & Hammond S.J. (1984): The structure of Cyanoginosin-LA, a cyclic heptapeptide toxin from the cyanobacterium Microcystis aeruginosa. J. Chem. Soc. Perkin Trans. 1: 2311-2318.

Bourke A.T.C. & Hawes R.B. (1983): Freshwater cyanobacteria (blue-green algae) and human health. Med. J. Aust. 1: 491-492.

Bourke A.T.C., Hawes, R.B., Neilson, A. & Stallman N.D. (1983): An outbreak of hepatoenteritis (the Palm islands mystery disease) possibly caused by algal intoxication. Toxicon 3: 45-48.

Bourne D.G., Jones G.J., Blakeley R.L., Jones A., Negri A. & Riddles P. (1996): Enzymatic pathway for the degradation of the cyanobacterial cyclic peptide toxin microcystin LR. Applied and Environmental Microbiology 62: 4086-4094.

Brettum, P. (1989): Alger som indikator på vannkvalitet. Planteplankton. Niva rapport 0-86116. NIVA 111 pp.

Brooks W.P. & Codd G.A. (1988): Immunoassay of hepatotoxic cultures and water blooms of cyanobacteria using Microcystis aeruginosa peptide toxin polyclonal anti-bodies. Environmental Technology Letters 9: 1343-1348.

Bruno M., Barbini D.A., Pierdominici E., Serse A.P. & Ioppolo A. (1994): Anatoxin-a and a previously unknown toxin in Anabaena planctonica from blooms found in lake Mulargia (Italy). Toxicon 32 (3): 369-373.

Campbell D.L., Lawton L.A., Beattie K.A. & Codd G.A. (1994): Comparative assessment of the specificity of the brine shrimp and microtox assays to hepatotoxic (microcystin-LR-containing) cyanobacteria. Environmental Toxicology and Water Quality: An International Journal 9: 71-77.

Carmichael W.W. (1988): Toxins of freshwater algae. - I: Tu A.T. (Ed.), Marine toxins and venoms. Handbook of natural toxins 3, Marcel Dekker Inc., New York, pp. 121-147.

Carmichael W.W. (1989): Freshwater cyanobacteria (blue-green algae) toxins. -I: Ownby C.L. & Odell G.V. (Eds.). Natural toxins. Characterization, Pharmacology and Therapeutics. Pergamon Press, Oxford. pp. 3-16.

Carmichael W.W. (1994): The toxins of cyanobacteria. Sci. Am. Z70: 78-86.

Carmichael W.W. (1996): Liver failure and human deaths at a haemodialysis centre in Brazil: microcystins as a major contributing factor. Harmful Algae News 15: 11.

Carmichael W.W., Beasley V., Bunner D.L., Eloff J.N., Falconer I., Gorham P., Harada K-I., Krishnamurthy T., Yu M-J., Moore R.E., Rinehart K., Runnegar M., Skulberg O.M. & Watanabe M. (1988a): Naming of cyclic heptapeptide toxins of cyanobacteria (blue-green algae). Toxicon 26 (11): 971-973.

Carmichael W.W., Evans W.R., Yin Q.Q., Bell P. & Moczydlowski E (1997): Evidence for paralytic shellfish poisons in the freshwater cyanobacterium Lyngbya wollei (Farlow ex Gomont) comb. nov. Applied and Environmental Microbiology, Aug. 1997, 63 (8): 3104-3110.

Carmichael W.W. & Falconer I.R. (1993): Diseases related to freshwater blue-green algal toxins, and control measures. - I: Falconer I.R. (Ed.) Algal toxins in seafood and drinking water. Academic Press, London, pp. 187-209.

Carmichael W.W. & Gorham P.R. (1978): Anatoxins from clones of Anabaena flosaquae isolated from lakes of western Canada. Mitt. Internat. Verein. Limnol. 21: 285-295.

Carmichael W.W., Jones C.L.A., Mahmood N.A. & Theiss W.C. (1985): Algal toxins and water based diseases. CRC Crit. Rev. Environ. Control 15: 275-313.

Carmichael W.W. & Mahmood N.A. (1984): Toxins of freshwater cyanobacteria. - I: Ragelis E.P. (Ed.) Seafood Toxins, ACS Symposium series, No. 262, American Chemical Society, pp. 377-389.

Carmichael W.W., Yu M-J., He Z-R., He J-W. & Yu J-L. (1988b): Occurence of the toxic cyanobacterium (blue-green alga) Microcystis aeruginosa in Central China. Arch. Hydrobiol. 114 (1): 21-30.

Chu F.S. & Fan T.S.L. (1985): Indirect enzymelinked immunosorbent assay for saxitoxin in shellfish. J. Ass. Off. Anal. Chem. 68:13-16.

Chu F.S., Huang X. & Wei R.D. (1990): Enzymelinked immunosorbent assay for microcystins in blue-green algal blooms. Assoc. Anal. Chem. 73: 451-456.

Chu F.S., Huang X., Wei R.D. & Carmichael W.W. (1989): Production and characterization of antibodies against microcystins. Applied and Environmental Microbiology 55 (8): 1928-1933.

Codd G.A. & Bell S.G. (1985): Eutrophication and toxic cyanobacteria. J. Water. Pollut. Control. 34: 225-232.

Codd G.A., Brooks W.P., Priestley I.M., Poon G.K., Bell S.G. & Fawell J.K. (1989): Production, detection, and quantification of cyanobacterial toxins. Toxicity Assessment 4: 499-511.

Cook W.O., Beasley V.R., Lovell R.A., Dahlem A.M., Hooser S.B., Mahmood N.A. & Carmichael W.W. (1989): Consistent inhibition of peripheral cholinesterases by neurotoxins from the freshwater cyanobacterium Anabaena flosaquae: Studies of ducks, swine, mice and a steer. Environmental Toxicology and Chemistry 8: 915-922.

Craig M., McCready T.L., Luu H.A., Smillie M.A., Dubord P. & Holmes C.F.B. (1993): Identification and characterization of hydrophobic microcystins in Canadian freshwater cyanobacteria. Toxicon 31 (12): 1541-1549.

Cronberg G. & Komárek J. (1994): Planktic cyanoprokaryotes found in South Swedish lakes during the XIIth international symposium on cyanophyte research, 1992. Algological Studies 75: 323-352.

Damsø L., Worm J., Henriksen P. & Moestrup Ø. (1994): Giftige blågrønalger i Danmark. Vand & Jord 1 (5): 195-198.

Dean A.G. & Jones T.C. (1972): Seasonal gastroentertis and malabsorption at an amerian military base in the Philippines. American Journal of Epidemiology 95 (2): 111-127.

Devlin J.P., Edwards O.E., Gorham P.R., Hunter N.R., Pike R.K. & Stavric B. (1977): Anatoxin-a, a toxic alkaloid from Anabaena flosaquae NCR-44h. Can. J. Chem. 55: 1367-1371.

Dillenberg H.O. & Dehnel M.K. (1960): Toxic waterbloom in Saskatchewan. 1959. Can. Med. Assoc. 63: 1-5.

Donati C., Drikas M., Hayes R. & Newcombe G. (1994): Microcystin-LR adsorption by powdered activated carbon. Water Research 28 (8): 1735-1742.

Edwards C., Beattie K.A., Scrimgeour C.M. & Codd G.A. (1992): Identification of anatoxin-a in benthic cyanobacteria (blue-green algae) and in associated dog poisonings at Loch Insh, Scotland. Toxicon 30 (10): 1165-1175.

Edwards C., Lawton L.A., Beattie K.A., Codd G.A., Pleasance S. & Dear G.J. (1993): Analysis of microcystins from cyanobacteria by liquid chromatography with mass spectrometry using atmosphaeric-pressure ionization. Rapid Communications in Mass Spectrometry 7: 714-721.

Ellman G.L., Courtney D.K., Andres V. & Featherstone R.M. (1961): A new and rapid colorimetric determination of acetylcholinesterase activity. Biochemical Pharmacology 7: 88-95.

El-saadi O., Esterman A.J., Cameron S.& Roder D.M. (1995): Murray river water, raised cyanobacterial cell counts, and gastrointestinal and dermatological symtoms. The midical journal of australia, 162: 122-125.

Eriksson J.E., Meriluoto J.A.O., Kujari H.P., Österlund K., Fagerlund K. & Hällbom L. (1988): Preliminary characterization of a toxin isolated from the cyanobacterium Nodularia spumigena. Toxicon 26 (2): 161-166.

Eriksson J.E., Meriluoto J.A.O. & Lindholm T. (1989): Accumulation of peptide toxin from the cyanobacterium Oscillatoria agardhii in the freshwater mussel Anadonta cygnea. Hydrobiologia 183: 211-216.

Eriksson J.E., Toivola D., Meriluoto J.A.O., Karaki H., Han Y-G. & Hartshorne D. (1990): Hepatocyte deformation induced by cyanobacterial toxins reflects inhibition of protein phosphatases. Biochemical and Biophysical Research Communications 173 (3): 1347-1353.

Falconer I.R. (1991): Tumor promotion and liver injury caused by oral consumption of cyanobacteria. Environmental Toxicology and Water Quality: An International Journal 6: 177-184.
Falconer I.R. (1993): Measurement of toxins from blue-green algae in water and foodstuffs. - I: Falconer I.R. (Ed.): Algal toxins in seafood and drinking water. University of Adelaide, Australia. Academic press.

Falconer I.R., Beresford A.M. & Runnegar M.T.C. (1983a): Evidence of liver damage by toxin from a bloom of the blue-green alga, Microcystis aeruginosa. The Medical Journal of Australia 1: 511-514.

Falconer I.R., Burch M.D., Steffensen D.A., Choice M. & Coverdale O.R. (1994): Toxicity of the blue-green alga (cyanobacterium) Microcystis aeruginosa in drinking water to growing pigs, as an animal model for human injury and risk assessment. Environmental Toxicology and Water Quality, 9: 131-139.

Falconer I.R. & Humpage A.R. (1996): Turnover promotion by cyanobacterial toxins. Phycologia 35: 74-79.

Falconer I.R., Runnegar M.T.C., Buckley T., Huyn V.L. & Bradshaw P. (1989): Using activated carbon to remove toxicity from drinking water containing cyanobacterial blooms. J. Am. Water Works Assoc. 18: 102-105.

Falconer I.R., Runnegar M.T.C. & Huyn V.L. (1983b): Effectiveness of activated carbon in the removal of algal toxin from potable water supplies: A pilot plant investigation. - I: Australian Water and Wastewater Association, Tenth Federal Convention, Sydney, April Technical Papers: 261-268.

Falconer I.R., Smith J.V., Jackson A.R.B., Jones A. & Runnegar M.T.C. (1988): Oral toxicity of a bloom of the cyanobacterium Microcystis aeruginosa administered to mice over periods up to 1 year. Journal of Toxicology and Environmental Health 24: 291-305.

Flett D.J., Nicholson B.C. & Burch M.D. (1991): Analysis of peptide toxins from cyanobacteria using high performance liquid chromatography (HPLC). Technical Papers, Australian Water & Wastewater Association, 14th federal convention, pp. 86-93.

Francis G. (1878): Poisonous Australian lake. Nature 18: 11-12.

Fujiki H., Suganuma M., Hakii H., Bartolini G., Moore R.E., Takegama S. & Sugimura T. (1984): A two-stage mouse skin carcinogenesis study of lyngbyatoxin A. Journal of Cancer Research and Clinical Oncology 108: 174-176.

Fujiki H., Suganuma M., Suguri H., Yoshizawa S., Takagi K., Nakayasu M., Ojika M., Yamada K., Yasumoto T., Moore R.E. & Sugimura T. (1990): New tumor promoters from marine natural products. -I: Marine Toxins: Origin, Structure and Molecular Pharmacology, Vol. 418 (Ed. by S. Hall & G. Strichartz), pp. 232-240. American Chemical Society, Washington, DC.

Fyns Amt (1991): Vandmiljø overvågning. Lange Sø 1990. 85 pp.

Gorham P.R. (1962): Laboratory studies on the toxins produced by water blooms of blue-green algae. Am J. Public Health 52: 2100- 2105.

Gorham P.R. & Carmichael W.W. (1988): Hazards of freshwater blue-green algae (cyanobacteria). -I: Lembi C.A. & Warland J.R., (Eds.). Algae and human affairs. Cambridge University Press, Cambridge, pp. 403-431.

Hammer U.T. (1968): Toxic blue-green algae in Saskatchewan. Can. Vet. J. 9: 221-229.

Harada K-I., Kimura Y., Ogaea K., Suzuki M., Dahlem A.M., Beasley V.R. & Carmichael W.W. (1989): A new procedure for the analysis and purification of naturally occuring anatoxin-a from the blue-green alga Anabaena flosaquae. Toxicon 27 (12): 1289-1296.

Harada K-I., Nagai H., Kimura Y., Suzuki M., Park H-D., Watanabe M.F., Luukkainen R., Sivonen K. & Carmichael W.W. (1993): Liquid chromatography/mass spectrometric detection of anatoxin-a, a neurotoxin from cyanobacteria. Tetrahedron 49 (41): 9251-9260.

Harada K-I., Ogawa K., Kimura Y., Murata H., Suzuki M., Thorn P.M., Evans W.R. & Carmichael W.W. (1991(a)): Microcystins from Anabaena flosaquae NRC 525-17. Chem. Res. Toxicol. 4: 534-540.

Harada K-I., Ogawa K., Matsuura K., Nagai H., Murata H., Suzuki M., Itezono Y., Nakayama N., Shirai M. & Nakano M. (1991(b)): Isolation of two toxic heptapeptide microcystins from an axenic strain of Microcystis aeruginosa, K-139. Toxicon 29 (4/5): 479-489.

Harada K-I., Suzuki M., Dahlem A.M., Beasley V.R., Carmichael W.W., Rinehart K.L. (1988): Improved method for purification of toxic peptides produced by cyanobacteria. Toxicon 26 (5): 433-439.

Haugen J.E., Skulberg O.M., Andersen R.A., Alexander J., Lilleheil G., Gallagher T. & Brough P.A. (1994): Rapid analysis of cyanophyte neurotoxins: An improved method for quantitative analysis of anatoxin-a and homoanatoxin-a in the sub-ppb to ppb range. Algological studies 75: 111-121.

Hawkins P.R., Runnegar M.T., Jackson A.R.B. & Falconer I.R. (1985): Severe hepatotoxicity caused by the tropical cyanobacterium (blue-green alga) cylindrospermopsis raciborskii (Woloszynska) seenaya and subba raju isolated from a domestic water supply reservoir. Applied and Environmental Microbiology 5: 1292-1295.

Hawser S.P., Codd G.A., Carpenter E.J. & Capone D.G. (1991): A neurotoxic factor associated with the bloom forming cyanobacterium Trichodesmium. Toxicon 29 (3): 277-278.

Hayman J. (1992): Beyond the Barcoo - probable human tropical cyanobacterial poisoning in outback Australia. The Medical Journal of Australia 157: 794-796.

Heise H.A. (1949): Symptoms of hay fever caused by algae. Journal of Allergy 20: 383-385.

Heise H.A. (1951): Symptoms of hay fever caused by algae. II. Microcystis. Another form of algae producing allergenic reactions. Annals of Allergy 9: 100-101.

Henning M. & Kohl J.G. (1981): Toxic blue-green algae water blooms found in some lakes in the German Democratic Republic. Int. Revue Ges. Hydrobiol. 66: 553-561.

Henriksen P., Carmichael W.W., An J. & Moestrup Ø. (1997): Detection of an anatoxin-a(s)-like anticholinesterase in natural blooms and cultures of cyanobacteria/blue-green algae from Danish lakes and in the stomach contents of poisoned birds. Toxicon 35: 901-913.

Henriksen P. & Moestrup Ø. (1997). Seasonal variations in microcystin contents of Danish cyanobacteria. Natural Toxins 5: 99-106.

Himberg K. (1989): Determination of anatoxin-a, the neurotoxin of Anabaena flosaquae cyanobacterium, in algae and water by gas chromatography-mass spectrometry. Journal of Chromatography 481: 358-362.

Holmes C.F.B. (1991): Liquid chromatography-linked protein phosphatase bioassay; A highly sensitive marine bioscreen for okadaic acid and related diarrhetic shellfish toxins. Toxicon 29 (4/5): 469-477.

Holmes C.F.B., McCready T.L., Craig M., Lambert T.W. & Hrudey S.E. (1994): A sensitive bioscreen for detection of cyclic peptide toxins of the microcystin class. - I: Codd G.A., Jefferies T.M., Keevil C.W. & Potter E. (Eds.) Detection methods for cyanobacterial toxins. The Royal Society of Chemistry, Cambridge, pp. 85-89.

Humpage A.R., Rositano J., Baker P.D., Nicholson B.C., Steffensen D.A., Bretag A.H. & Brown R.K. (1993): Paralytic shellfish poisons from freshwater blue-green algae. The Medical Journal of Australia 159: 423.

Humpage A.R., Rositano J., Bretag A.H., Brown R., Baker P.D., Nicholson B.C. & Steffensen D.A. (1994): Paralytic Shellfish Poisons from Australian cyanobacterial blooms. Australian Journal of Marine and Freshwater Research 45: 761-771.

Ikawa M., Wegener K., Foxall T.L. & Sasner J.J. (1982): Comparison of the toxins of the blue-green alga Aphanizomenon flosaquae with the Gonyaulax toxins. Toxicon 20 (4): 747-752.

James H.A., James C.P. & Hart J. (1994): The analysis of microcystin-LR in water: Application in water treatment studies. in Detection methods for cyanobacterial toxins ed. G.A. Codd, T.M. Jefferies, C.W. Keevil and E. Potter. The Royal Society of Chemistry.

James K.J., Furey A., Sherlock I.R., Stack M.A., Twohig M., Caudwell F.B. & Skulberg O.M. (1998): Sensitive determination of anatoxin-a, homoanatoxin-a and their degradation products by liquid chromatography with fluorimetric detection. Journal of Chromatography A 798: 147-157.

Jellet J.F, Stewart, L.E. & Laycock M.C. (1995): Toxicological evaluation of saxitoxin, neosaxitoxin, gonyautoxin II, gonyautoxin II plus III and decarbamoylsaxitoxin with the mouse neuroblastoma cell bioassay. Toxic. in Vitro 9: 57-65.

Jensen, J.P., E. Jeppesen, P. Kristensen & K. Olrik (1994): Impact of nutrients and physical factors on the shift from cyanobacterial to chlorophyte dominance in shallow Danish lakes. Can. J. Fish. Aquat. Sci. 51: 1692-99.

Jensen, J.P & M. Søndergaard (1994): Interkalibrering af planteplanktonundersøgelser i søer. Teknisk anvisning fra DMU nr. 8. Danmarks Miljøundersøgelser. 40 pp.

Jeppesen, E, J.P. Jensen, P. Kristensen, M. Søndergaard, E. Mortensen, O. Sortkjær & K. Olrik (1990): Fish manipulation as a lake restoration tool in shallow, eutrophic temperate lakes. 2: threshold, levels, longterm stability and conclusions. Hydrobiologia 200/201: 219-227.

Jochimsen E.M., Carmichael W.W., An J., Cardo D.M., Cookson S.T., Holmes C.E.M., Antunes M.B.C., de Melo Filho D.A., Lyra T.M., Barreto V.S.T., Azevedo S.M.F.O. & Jarvis W.R. (1998): Liver failure and death after exposure to microcystins at a hemodialysis center in Brazil. The New England Journal of Medicine 338: 873-878.

Jones G.J. & Negri A.P. (1997): Persistence and degradation of cyanobacterial paralytic shellfish poisons (PSPs) in freshwaters. Water Research 31: 525-533.

Jones G.J. & Orr P.T. (1994): Release and degradation of microcystin following algicide treatment of a Microcystis aeruginosa bloom in a recreational lake, as determined by HPLC and protein phosphatase inhibition assay. Water Research 28 (4): 871-876.

Jones G.J., Bourne D.G., Blakeley R.L. & Doelle H. (1994): Degradation of the cyanobacterial hepatotoxin microcystin by aquatic bacteria. Natural Toxins 2: 228-235.

Jongman, R.H.G., C.J.F. ter Braak & O.F.R. van Tongeren (Eds.) (1987): Data analysis in community and landscape ecology. Pudoc Wageningen. 299 pp.

Kangatharalingam N. & Priscu J.C. (1993): Isolation and verification of anatoxin-a producing clones of Anabaena flosaquae (Lyngb.) de Breb. from a eutrophic lake. FEMS Microbiology Ecology 12: 127-130.

Kaya K. & Sano T. (1998). A photodetoxification mechanism of the cyanobacterial hepatotoxin microcystin-LR by ultraviolet irradiation. Chemical Research in Toxicology 11: 159-163.

Kaya K. & Watanabe M.M. (1990): Microcystin composition of an axenic clonal strain of Microcystis viridis and Microcystis viridis containing waterblooms in Japanese freshwaters. J. Appl. Phycol. 2: 173-178.

Keijola A.M. (1988): Removal of cyanobacterial toxins in water treatment processes: Laboratory and pilotscale experiments. Toxicity assessment: An international journal 3: 643-656.

Keleti G. & Sykora J.L. (1982): Production and proporties of cyanobacterial endotoxins. Applied and Environmental Microbiology 43: 104-109.

Kfir R., Johannsen E. & Botes D.P. (1986): Monoclonal antibody specific for cyanoginosin-LA: preparation and characterization. Toxicon 24: 543-552.

Kiviranta J., Namikoshi M., Sivonen K., Evans W.R., Carmichael W.W. & Rinehart K.L. (1992): Structure determination and toxicity of a new microcystin from Microcystis aeruginosa strain 205. Toxicon 30 (9): 1093-1098.

Kiviranta J., Sivonen K., Lathi K., Luukkainen R. & Niemelä S.I. (1991a): Production and biodegradation of cyanobacterial toxins - a laboratory study. Arch. Hydrobiol. 121 (3): 281-294.

Kiviranta J., Sivonen K., Niemelä S.I. & Huovinen K. (1991b): Detection of toxicity of cyanobacteria by Artemia salina bioassay. Environmental Toxicology and Water Quality: 6: 423-436.

Kononen K., Sivonen K. & Lehtimäki J. (1993): Toxicity of phytoplankton blooms in the Gulf of Finland and Gulf of Bothnia, Baltic Sea. - I: Smayda T.J. & Shimizu Y. (Ed-s.) Toxic Phytoplankton Blooms in the Sea. Elsevier, pp. 269-273.

Konst H., Mckercher P.D., Gorham P.R., Robertson A. & Howell J. (1965): Symptoms and pathology produced by toxic Microcystis aeruginosa NRC-1 in la boratory and domestic animals. Can. J. Comp. Med. Vet. Science 29: 221-228.

Kotaki Y., Oshima Y. & Yasumoto T.(1985): Bacterial transformation of paralytic shellfish toxins. -I: Andersen, D.M., White A.W. & Baden D.G. (eds). Toxic Dinoflagellates (Elsevier): 287-292.

Krishnamurthy T., Carmichael W.W. & Sarver E.W. (1986): Toxic peptides from freshwater cyanobacteria (blue-green algae). I. Isolation, purification and characterization of peptides from Microcystis aeruginosa and Anabaena flosaquae. Toxicon 24 (9): 865-873.

Krisnamurthy T., Szafraniec L., Hunt D.F., Shabanowitz J., Yates III J.R., Hauer C.R., Carmichael W.W., Skulberg O.M., Codd G.A. & Missler S. (1989): Structural characterization of toxic cyclic peptides from blue-green algae by tandem mass spectrometry. Proc. Natl. Acad. Sci. USA 86: 770-774.

Kristensen, P., J.P. Jensen & E. Jeppesen (1990a): Eutrofieringsmodeller for søer. NPo-forskning fra Miljøstyrelsen Nr. C9. 120 pp.

Kristensen , P., M. Søndergaard, E. Jeppesen, E. Mortensen & Aa. Rebsdorf. (1990b): Overvågningsprogram - Prøvetagning og analysemetoder i søer. Teknisk anvisning fra DMU nr. 1. Danmarks Miljøundersøgelser. 32 pp.

Kristiansen, J. (1966): Nogle midtjyske søers planteplankton i relation til eutrofigrad og kulturpåvirkning. Vättenhygien 22: 11-15.

Kusumi T., Ooi T., Watanabe M.M., Takahashi H & Kakisawa H. (1987): Cyanoviridin RR, a toxin from the cyanobacterium (blue-green alga) Microcystis viridis. Tetrahedron Letters 28 (40): 4695-4698.

Lakshmana Rao P.V. & Bhattacharya R. (1996): The cyanobacterial toxin microcystin-LR induced DNA damage in mouse liver in vivo. Toxicology 114: 29-36.

Lambert T.W., Boland M.P., Holmes C.F.B. & Hrudey S.E. (1994): Quantification of the microcystin hepatotoxins in water at environmentally relevant concentrations with the protein phosphatase bioassay. Environ. Sci. Technol. 26: 753-755.

Lanaras T., Tsitsamis S., Chlichlia C. & Cook C.M. (1989): Toxic cyanobacteria in Greek freshwaters. J. Appl. Phycol. 1: 67-73.

Lahti K. & Hiisvirta L. (1989): Removal of cyanobacterial toxins in water treatment processes: review of studies conducted in Finland. Water Supply 7: 149- 154.

Larsen J., Hansen P.J. & Ravn H. (1993): Giftige alger i danske farvande. Havforskning fra Miljøstyrelsen, nr. 28.

Lawton L.A., Beattie K.A., Hawser S.P., Campbell D.L. & Codd G.A. (1994a): Evaluation of assay methods for the determination of cyanobacterial hepatotoxicity. - I: Codd G.A., Jefferies T.M., Keevil C.W. & Potter E. (Eds.) Detection methods for cyanobacterial toxins. The Royal Society of Chemistry, Cambridge, pp. 111-116.

Lawton L.A., Campbell D.L., Beattie K.A. & Codd G.A. (1990): Use of a rapid bioluminescence assay for detecting cyanobacterial microcystin toxicity. Letters in Applied Microbiology 11: 205-207.

Lawton L.A. & Codd G.A. (1991): Cyanobacterial (blue-green algal) toxins and their significance in UK and European waters. Journal of the Institution of Water and Environmental Management 5 (1): 460-465.

Lawton L.A., Edwards C. & Codd G.A. (1994b): Extraction and high-performance liquid chromatographic method for the determination of microcystins in raw and treated waters. Analyst 119: 1525-1530.

Leeuwangh P., Kappers F.I., Dekker M. & Koerselman W. (1983): Toxicity of cyanobacteria in Dutch lakes and reservoirs. Aquatic Toxicology 4: 63-72.

Lepistö L., Lathi K., Niemi J. & Färdig M. (1994): Removal of cyanobacteria and other phytoplankton in four Finnish water-works. Algological Studies 75: 167-181.

Lillie, R.A., R. Last, P. Garrison, P. Rasmussen & J.W. Mason. (1993): A survey of the summer communities of 579 Wiconsin lakes. Trans. Wis. Acad. Sci., Arts and lett. 60: 125-45.

Lindholm T., Eriksson J.E. & Meriluoto J.A.O. (1989): Toxic cyanobacteria and water quality problems-examples from a eutrophic lake on Åland, South West Finland. Water Research 23 (4): 481-486.

Lindholm T. & Meriluoto, J.A.O. (1991): Recurrent Depth Maxima of the Hepatotoxic Cyanobacterim Oscillatoria agardhii. Can. J. Fish. Aquat. Sci. 48: 1629-1634.

Louzao M.C., Alfonso A., Botana A.M., Goenaga X., Cabado A.G. Vieyttes M.R. & Botana L.M. (1994a): Effect of lyophilization on the stability of gonyautoxins obtained from contaminated mussels. Toxicon 32( 7): 807-817.

Louzao M.C., Alfonso A., Cabado A.G. Botana A.M., Goenaga X., Vieytes M.R. & Botana L.M. (1994b): Fresenius Journal of Analytical Chemistry 349: 465-468.

Luukkainen R., Namikoshi M., Sivonen K., Rinehart K.L. & Niemelä S.I. (1994): Isolation and identification of 12 microcystins from four strains and two bloom samples of Microcystis spp.: structure of a new hepatotoxin. Toxicon 32 (1): 133-139.

Luukkainen R., Sivonen K., Namikoshi M., Färdig M., Rinehart K.L. & Niemelä S.I. (1993): Isolation and identification of eight microcystins from thirteen Oscillatoria agardhii strains and structure of a new microcystin. Appl. Envir. Microbiol. 59: 2204-2209.

MacKintosh C., Beattie K.A., Klumpp S., Cohen P. & Codd G.A. (1990): Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants. FEBS Letters 264 (2): 187-192.

MacKintosh C. & MacKintosh R.W. (1994): The inhibition of protein phosphatases by toxins: implications for health and an extremely sensitive and rapid bioassay for toxin detection. - I: Codd G.A., Jefferies T.M., Keevil C.W. & Potter E. (Eds.) Detection methods for cyanobacterial toxins. The Royal Society of Chemistry, Cambridge, pp. 90-99.

Mahmood N.A. & Carmichael W.W. (1986): Paralytic shellfish poisons produced by the freshwater cyanobacterium Aphanizomenon flosaquae NH-5. Toxicon 24 (2): 175-186.

Mahmood N.A., Carmichael W.W. & Pfahler D. (1988): Anticholinesterase poisonings in dogs from a cyanobacterial (blue-green algae) bloom dominated by Anabaena flosaquae. Am. J. Vet. Res. 49 (4): 500-503.

Matsunaga S., Moore R.E., Niemczura W.P. & Carmichael W.W. (1989): Anatoxin-a(s), a potent anticholinesterase from Anabaena flosaquae. J. Am. Chem. Soc. 111: 8021-8023.

Mattson R. & Willén T. (1986): Toxinbildande blågröna alger i svenska insjöer 1985. Naturvårdsverket rapport 3096, (2)/1986. Laboratoriet för miljökontroll. Uppsala. 26 pp.

Meriluoto J.A.O. & Eriksson J.E. (1988): Rapid analysis of peptide toxins in cyanobacteria. Journal of Chromatography 438: 93-99.

Meriluoto J.A.O., Isaksson K., Soini H., Nygård S.E. & Eriksson J.E. (1990): Retention mechanisms and selectivity in internal surface reversed-phase liquid chromatography. Studies with Cyanobacterial peptide toxins. Chromatographia 30: 301-308.

Meriluoto J.A.O., Sandström A., Eriksson J.E., Remaud G., Grey Craig A. & Chattopadhyaya J. (1989): Structure and toxicity of a peptide hepatotoxin from the cyanobacterium Oscillatoria agardhii. Toxicon 27: 1021-1034.

Mez K., Beattie K.A., Codd G.A., Hanselmann K., Hauser B., Naegeli H. & Preisig H.R. (1997): Identification of a microcystin in benthic cyanobacteria linked to cattle deaths on alpine pastures in Switzerland. Eur. J. Phycol. 32: 111-117.

Miljøstyrelsen (1993): Aquatic environment nationwide monitoring programme 1993-1997. Redegørelse fra Miljøstyrelsen nr. 3. 1993. 172 pp.

Namikoshi M., Choi B.W., Sakai R., Sun F., Rinehart K.L., Carmichael W.W., Evans W.R., Cruz P., Munro M.H.G. & Blunt J.W. (1994): New nodularins: A general method for structure assignment. J. Org. Chem. 59: 2349-2357.

Namikoshi M., Sivonen K., Evans W.R., Carmichael W.W., Rouhianen L., Luukkainen R. & Rinehart K.L. (1992(b)): Structures of three new homothyrosine-containing micro-cystins and a new homophenylalanine variant from Anabaena sp. strain 66. Chem. Res. Toxicol. 5: 661-666.

Namikoshi M., Sivonen K., Evans W.R., Carmichael W.W., Sun F., Rouhianen L., Luukkainen R. & Rinehart K.L. (1992(c)): Two new L-serine variants of micro-cystins-LR and -RR from Anabaena sp. strains 202 A1 and 202 A2. Toxicon 30 (11): 1457-1464.

Namikoshi M., Sivonen K., Evans W.R., Sun F., Carmichael W.W. & Rinehart K.L. (1992(a)): Isolation and structures of microcystins from a cyanobacterial water bloom (Finland). Toxicon 30 (11): 1473-1479.

Negri, A.P. & Jones G.J. (1995): Bioaccumulation of paralytic shellfish poisoning (PSP) toxins from the cyanobacterium Anabaena circinalis by the freshwater mussel Alathyria condola.

Nehring S. (1993): Mortality of dogs associated with a mass development of Nodularia spumigena (cyanophyceae) in a brackish lake at the German North Sea coast. J. Plankton Res. 13: 867-872.

Neumann U. & Weckesser J. (1998): Elimination of microcystin peptide toxins from water by reverse osmosis. Environmental Toxicology and Water Quality 13: 143-148.

Nicholson B.C., Rosinato J. & Burch M.D. (1994): Destruction of cyanobacterial peptide hepatotoxins by chlorine and chloramine. Wat. Res. 28: 1297-1303.

Nishiwaki-Matsushima R., Ohta T., Nishiwaki S., Suganuma M., Kohyama K., Ishikawa T., Carmichael W.W. & Fujiki H. (1992): Liver tumor promotion by the cyano-bacterial cyclic peptide toxin micro-cystin-LR. J. Cancer Res. Clin. Oncol. 118: 420-424.

NRA (1990): Toxic blue-green algae. National Rivers Authority. Water Quality Series No. 2.

Nygaard, G. (1949): Hydrobiological studies on some Danish ponds and lakes. Biol. Skr. Dan. Vidensk. Selsk. 7: 1-239.

Ohren J.A. (1988): Renseeffekter for alger og algetoksiner i direkte filtrering. Vann 1: 159-166.

Ohta T., Sueoka E., Iida N., Komori A., Suganuma M., Nishiwaki R., Tatematsu M., Kim S.-J., Carmichael W.W. & Fujiki H. (1994): Nodularin, a potent inhibitor of protein phosphatases 1 and 2A, is a new environmental carcinogen in male F344 rat liver. Cancer Research 54: 6402-6406.

Ojanperä I., Pelander A., Vuori E., Himberg K., Warris M. & Niinivaara K. (1995): Detection of cyanobacterial hepatotoxins by TLC. Journal of Planar Chromatography 8: 69-72.

Olrik, K. (1978): Cyanophyceae and environmental factors in 15 Danish lakes. Verh. Int. Limnol. 20: 690-95.

Olrik, K. (1991): Planteplankton - metoder. Miljøprojekt nr. 187. Miljøstyrelsen. 108 pp.

Olson T.A. (1960): Water poisoning - a study of poisonous algae blooms in Minnesota. Am. J. Public Health 50: 883-884.

Onodera H., Oshima Y., Henriksen P. & Yasumoto T. (1997): Confirmation of anatoxin-a(s), in the cyanobacterium Anabaena lemmermannii, as the cause of bird kills in Danish lakes. Toxicon 35: 1645-1648.

Ooi T., Kusumi T., Kakisawa H. & Watanabe M.M. (1989): Structure of cyanoviridin RR, a toxin from the blue-green alga, Micro-cystis aeruginosa. J. Appl. Phycol. 1: 31-38.

Oshima Y., Sugino K. & Yasumoto T. (1989): Latest advance in HPLC analysis of paralytic shellfish toxins. -I: Natori S., Hashimoto K., & Ueno Y. (eds.): Mycotoxins and phytotoxins (Elsevier): 319-326.

Othani I., Moore R.E. & Runnegar M.T.C. (1992): Cylindrospermopsin: A potent hepato-toxin from the blue-green alga Cylindrospermopsis raciborskii. J. Am. Chem. Soc. 114: 7941-7942.

Painuly P., Perez R., Fukai T. & Shimizu Y. (1988): The structure of a cyclic peptide toxin, cyanogenosin-RR from Microcystis aeruginosa. Tetrahedron Letters 29 (1): 11-14.

Park H-D., Watanabe M.F., Harada K-I., Nagai H., Suzuki M., Watanabe M. & Hayashi H. (1993): Hepatotoxin (microcystin) and neurotoxin (anatoxin-a) contained in natural blooms and strains of cyanobacteria from Japanese fresh-waters. Natural Toxins 1: 353-360.

Patrick, S.T. & N.J. Anderson (Eds.) (1995): Ecology and palaeoecology of lake eutrophication. An informal workshop, Salten Skov, Silkeborg, May 14-18, 1994. Geological Survey of Denmark. 65 pp.

Pearsal, W.-H. (1932): Phytoplankton in English lakes. II. The composition of the phytoplankton in relation .

Pelander A., Ojanpera I., Sivonen K., Himberg K., Warris M., Niinivaara K. & Vuori E. (1996): Screening for cyanobacterial toxins in bloom and strain samples by thin layer chromatography. Water Research 30: 1464-1470.

Pick, F.R. & D.R.S. Lean (1987): The role of macronutrients (C, N, P) in controlling cyanobacterial dominance in temperate lakes. N. Z. J. Mar. Freshwater Res. 21: 425-434.

Poon G.K., Priestley I.M., Hunt S.M., Fawell J.K. & Codd G.A. (1987): Purification procedure for peptide toxins from the cyano-bacterium Micro-cystis aeruginosa involving high-performance thin-layer chromatography. Journal of Chromatography 387: 551-555.

Prinsep M.R., Caplan F.R., Moore R.E., Patterson G.M.L., Honkanen R.E. & Boynton A.L. (1992): Microcystin-LA from a blue-green alga belonging to the stigonematales. Phytochemistry 31 (4): 1247-1248.

Rapala J., Sivonen K., Luukkainen R. & Niemelä S.I. (1993): Anatoxin-a concentration in Anabaena and Aphanizomenon under different environmental conditions and comparison of growth by toxic and non-toxic Anabaena-strains - a laboratory study. Journal of Applied Phycology 5: 581-591.

Ravn H., Anthoni U., Christophersen C., Nielsen P.H. & Oshima &. (1995): Standardized extraction method for paralytic shellfish toxins in phytoplankton. Journal of Applied Phycology 7: 589-594.

Raziuddin S., Siegelman H.W. & Tornabene T.G. (1983): Lipopolysaccharides of the cyanobacterium Microcystis aeruginosa. Eur. J. Biochem. 137: 333-336.

Repavich W.M., Sonzogni W.C., Standridge J.H., Wedepohl R.E. & Meisner L.F. (1990): Cyanobacteria (blue-green algae) in Wisconsin waters: acute and chronic toxicity. Water Research 24 (2): 225-231.

Reynolds, C.S. (1984): The ecology of freshwater phytoplankton. Cambridge University Press, Cambridge. 384 pp.

Reynolds, C.S. (1987): Cyanobacterial water-blooms. Adv. Bot. Res. 13: 67-143.

Richard D.S., Beattie K.A. & Codd G.A. (1983): Toxicity of cyanobacterial blooms from Scottish freshwaters. Environ. Technol. Lett. 4: 377-382.

Rinehart K.L., Namikoshi M. & Choi B.W. (1994): Structure and biosynthesis of toxins from blue-green algae (cyanobacteria). J. Appl. Phycol. 6: 159-176.

Rosén, G. (1981a): Tusen sjøar. Växtplanktons miljökrav. Statens Naturvårsverk, Stockholm. 119 pp.

Rosén, G. (1981b): Phytoplankton indicators and their relation to certain chemical and physical factors. Limnologica (Berl.) 13: 263-90.

Runnegar M.T.C., Andrews J., Gerbes R.G. & Falconer I.R. (1987): Injury to hepatocytes induced by a peptide toxin from the cyanobacterium Micro-cystis aeruginosa. Toxicon 25 (11): 1235-1239.

Runnegar M.T.C. & Falconer I.R. (1986): Effect of toxin from the cyano-bacterium Micro-cystis aeruginosa on ultrastructural morphology and actin polymerization in isolated hepatocytes. Toxicon 24 (2): 109-115.

Rylander R., Bake B., Fischer J.J. & Helander I.M. (1989): Pulmonary function and symptons after inhalation of endotoxin. American Review of Respiratory Disease 140:981-986.

Saadi O.E. & Cameron A.S. (1993): Illness associated with blue-green algae. Medical Journal of Australia 158: 792-793.

Saito S., Nakano Y., Kushida K., Shirai M., Harada K.-I. & Nakano M. (1994): Cross-reactivity and neutralizing ability of monoclonal antibodies against microcystins. Micro-biol. Immunol. 38 (5): 389-392.

SAS Institute (1989): SAS/Stat User's guide. Version 6, Fourth edition. Volume 1+2. 1686 pp.

Sas, H. (Ed.) (1989): Lake restoration by reduction of nutrient loading. Expectations, experiences, extrapolations. Academia Verlag-Richardz Gmbh. 497 pp.

Schreurs, H. (1992): Cyanobacterial dominance. Relations to eutrophication and lake morphology. Academisch proefschrift. Amsterdam. 198 pp.

Schwimmer M. & Schwimmer D. (1968): Medical aspects of phycology. -I: Jackson D.J. (Ed.): Algae, Man, and the Environment, Syracuse University Press, Syracuse, New York. pp. 278-358.

Scott W.E. (1991): Occurence and significance of toxic cyanobacteria in Southern Africa. Wat. Sci. Tech. 23: 175-180.

Seip, K.L. (1988): Et regelsystem for å identifisere innsjøers respons på reduksjoner av fosforbelastning. Del II. Forekomst af blågrønnalger (cyanobacteria). Limnos 3: 8-12.

Shapiro J. (1990): Current beliefs regarding dominance of blue-greens: the case for the importance of CO2 and pH. Verhandlungen Internationale Vereinigung für Theoretische und Angewandte Limnologie 24: 38-54.

Shimizu Y. (1987): Dinoflagellate toxins. -I: Taylor F.J.R. (Ed.): The biology of dinoflagellates (Botanical Monographs; V. 21). Blackwell Scientific Publications, pp. 282-315.

Shimizu Y. & Yoshioka M. (1981): Transformation of paralytic shellfish toxins as demonstrated in scallops homogenates. Science 212: 546-547.

Shirai M., Ohtake A., Sano T., Matsumoto S., Sakamoto T., Sato A., Aida T., Harada K-I., Shimada T., Suzuki M. & Nakano M. (1991): Toxicity and toxins of natural blooms and isolated strains of Microcystis spp. (cyano-bacteria) and improved procedure for purification of cultures. Applied and Environmental Microbiology 57 (4): 1241-1245.

Sim A.T.R. & Mudge L-M. (1993): Protein phosphatase activity in cyanobacteria: concequences for microcystin toxicity analysis. Toxicon 31 (9): 1179-1186.

Sivonen K. (1990a): Toxic cyanobacteria in Finnish fresh waters and the Baltic Sea. Academic dissertation in microbiology. Reports from departments of microbiology, University of Helsinki, 39/1990. 87 pp.
Sivonen K. (1990b): Effects of light, temperature, nitrate, orthophosphate, and bacteria on growth of and hepatotoxin production by Oscillatoria agardhii strains. Applied and Environmental Microbiology 56: 2658-2666.

Sivonen K. (1996): Cyanobacterial toxins and toxin production. Phycologia 35 (suppl.): 12-24.

Sivonen K., Carmichael W.W., Namikoshi M., Rinehart K.L., Dahlem A.M. & Niemelä S.I. (1990a): Isolation and characterization of hepatotoxic microcystin homologs from the filamentous freshwater cyanobacterium Nostoc sp. strain 152. Applied and Environmental Microbiology 56 (9): 2650-2657.

Sivonen K., Himberg K., Luukkainen R., Niemelä S.I., Poon G.K. & Codd G.A. (1989): Preliminary characterization of neurotoxic cyanobacteria blooms and strains from Finland. Toxicity Assessment: An International Journal 4: 339-352.

Sivonen K., Namikoshi M., Evans W.R., Carmichael W.W., Sun F., Rouhainen L., Luukkainen R. & Rinehart K.L. (1992a): Isolation and characterization of a variety of microcystins from seven strains of the cyanobacterial genus Anabaena. Applied and Environmental Microbiology 58 (8): 2495-2500.

Sivonen K., Namikoshi M., Evans W.R., Färdig M., Carmichael W.W. & Rinehart K.L. (1992b): Three new microcystins, cyclic heptapeptide hepatotoxins, from Nostoc sp. strain 152. Chem. Res. Toxicol. 5: 464-469.

Sivonen K., Namikoshi M., Evans W.R., Gromov B.V., Carmichael W.W. & Rinehart K.L. (1992c): Isolation and structure of five micro-cystins from a Russian Micro-cystis aeruginosa strain CALU 972. Toxicon 30 (11): 1481-1485.

Sivonen K., Niemelä S.I., Niemi R.M., Lepistö L., Luoma T.H. & Räsänen L.A. (1990b): Toxic cyano-bacteria (blue-green algae) in Finnish fresh and coastal waters. Hydrobiologia 190: 267-275.

Sivonen K., Skulberg O.M., Namikoshi M., Evans W.R., Carmichael W.W. & Rinehart K.L. (1992d): Two methyl ester derivatives of microcystins, cyclic heptapeptide hepato-toxins, isolated from Anabaena flosaquae strain CYA 83/1. Toxicon 30 (11): 1465-1471.

Skulberg O. (1988): Blågrønalger - Vannkvalitet, Norsk Institut for Vannforskning (NIVA). Oslo. 121 pp.

Skulberg O.M., Carmichael W.W., Andersen R.A., Matsunaga S., Moore R.E. & Skulberg R. (1992): Investigations of a neurotoxic Oscillatorialean strain (Cyanophyceae) and its toxin. Isolation and characterization of Homoanatoxin-a. Environmental Toxicology and Chemistry 11: 321-329.

Skulberg O.M., Carmichael W.W., Codd G.A. & Skulberg R. (1993): Taxonomy of toxic cyanophyceae (cyanobacteria). - I: Falconer I.R. (Ed.): Algal Toxins in seafood and drinking water. Academic Press Limited, London, pp. 145-164.

Skulberg O.M., Underdal B. & Utkilen H. (1994): Toxic waterblooms with cyanophytes in Norway - current knowledge. Algological Studies 75: 279-289.

Smith, V.H. (1983): Low nitrogen to phosphorus ratios favour dominance by by blue-green algae in lake phytoplankton. Science (Wash. D.C.) 121: 669-71.

Smith, V.H. (1985): Predictive models for the biomass of blue-green algae in lakes. Water Resour. Bull. 21: 433-39.

Smith, V.H. (1986): Light and nutrient effect on the relative biomass of blue-green algae in lake phytoplankton. Can. J. Fish. Aquat. Sci. 43: 148-53.

Smith, V.H. (1990): Phytoplankton responses to eutrophication in inland waters. p. 231-49. -I: Akatsuka I. (Ed.): An introduction to applied phycology. Academic Publishing bv. The Hague.

Smith, V.H, E. Willen & B. Karlsson (1987): Predicting the summer peak biomass of four species of blue-green algae (Cyanophyta/Cyanobacteria) in Swedish lakes. Water Resour. Bull. 23: 397-402.

Steinberg, C. & H. Hartmann (1988): Planctonic bloom-forming cyanobacteria and the eutrophication of rivers and lakes. Freshwater Biol. 20: 279-87.

Stevens D.K. & Krieger R.I. (1991): Stability studies on the cyanobacterial nicotinic alkaloid anatoxin-a. Toxicon 29 (2): 167-179.

Stotts R.R., Namikoshi M., Haschek W.M., Rinehart K.L., Carmichael W.W., Dahlem A.M. & Beasley V.R. (1993): Structual modifications imparting reduced toxicity in micro-cystins from Micro-cystis spp. Toxicon 31 (6): 783-789.

Sullivan J.J. (1990): High-performance liquid chromatographic method applied to paralytic shellfish poisoning research. - I: Marine Toxins: Origin, structure and molecular pharmacology, American Chemical Society, Washington, pp. 66-77.

Sullivan J.J., Iwaoka W.T. & Liston J. (1983): Enzymatic transformation of PSP-toxins in the little neck clam (Protothaca staminea). Biochem. Biophys. Comm. 144: 465-472.

Sullivan J.J. & Wekell M.M. (1984): Determination of paralytic shellfish poisoning toxins by high pressure liquid chromatography. -I: Ragelis E.P. (Ed.): Seafood Toxins. American Chemical Society, Washington D.C., pp. 197-205.

Sullivan J.J. & Wekell M.M. (1986): The application of high performance liquid chromatography in a paralytic shellfish monitoring program, Seafood Quality Determination. -I: Kramer & Liston (Eds.): Proceeding of an International Symposium Coordinated by the University of Alaska. Anchorage, Alaska, pp. 357-371.

Takahashi S. & Kaya K. (1993): Quail spleen is enlarged by microcystin RR as a blue-green algal hepatotoxin. Natural Toxins 1: 283-285.

Tchernajenko V.M. (1994): Cyclic peptide hepatotoxins from fresh water cyanobacteria water blooms collected in the river Dnieper reservoirs and other water bodies from the European part of Russia. - I: Codd G.A., Jefferies T.M., Keevil C.W. & Potter E. (Eds.): Detection methods for cyanobacterial toxins. The Royal Society of Chemistry, Cambridge, pp. 19-23.

ter Braak, C.J.F. (1987): Unimodel models to species to environment. Doctoral thesis, University of Wageningen. 152 pp.

ter Braak, C.J.F. (1988): CANOCO - a Fortran program for canonical community ordination by (partial) (detrended) (canonical) correspondence analysis, principal components analysis and redundancy analysis (version 2.1) Technical report LWA-88-02, GLW, Wageningen. 95 pp.

ter Braak, C.J.F. (1990): Update notes: CANOCO version 3.10. Agricultural mathematics group. Wageningen. 35 pp.

ter Braak, C.J.F., S. Juggins, H.J.B. Birks & H. van der Voet (1993): Weigted averaging partial least squares regression (WA-PLS): definition and comparison with other methods for speciesenvironment calibration.
- I: Patil G.P. & Rao C.R. (Eds.): A Multivariate environmental statistics. North Holland, p. 529-60.

Terao K., Igarashi K., Ohtani I., Watanabe M.F., Harada K.-I., Ito E. & Watanabe M. (1994): Electron microscopic studies on experimental poisoning in mice induced by cylindrospermopsin isolated from blue-green alga Umezakia natans. Toxicon 32: 833-843.

Thunmark, S. (1945): Zur soziologie des Süsswasserplanktons. Fol. Limnol. Scand. 3: 1-66.

Tilman D., Kilham S.S. & Kilham P. (1982): Phytoplankton community ecology: the role of limiting nutrients. Ann. Rev. Ecol. System 13: 375-83.

Trifinova, I.S. (1989): Changes in community structure and productivity of lake phytoplankton as indicators of lake and reservoir eutrophication. Arch. Hydrobiol. Beih. Ergebn. Limnol. 33: 363-71.

Trimbee, A.M. & E.E. Prepas. (1987): Evaluation of total phosphorus as a predictor of the relative biomass of blue-green algae with special emphasis on Alberta lakes. Can. J. Fish. Aquat. Sci. 44: 1337-42.

Tsuji K., Naito S., Kondo F., Ishikawa N., Watanabe M.F., Suzuki M. & Harada K-I. (1994): Stability of microcystins from cyano-bacteria: Effect of light on decomposition and isomerization. Environ. Sci. Technol. 28: 173-177.

Tsuji K., Watanuki T., Kondo F., Watanabe M.F., Suzuki S., Nakazawa H., Suzuki M., Uchida H. & Harada K.-I. (1995): Stability of microcystins from cyanobacteria (2): effect of UV light on decomposition and isomerization. Toxicon 33: 1619-1631.

Turner P.C., Gammie A.J., Hollinrake K. & Codd G.A. (1990): Pneumonia associated with contact with cyanobacteria. British Medical Journal 300: 1440-1441.

Ueno Y., Nagata S., Tsutsumi T., Hasegawa A., Watanabe M.F., Park H.-D., Chen G.-C., Chen G. & Yu S.-Z. (1996): Detection of microcystins, a blue-green algal hepatotoxin, in drinking water sampled in Haimen and Fusui, endemic areas of primary liver cancer in China, by highly sensitive immunoassay. Carcinogenesis 17: 1317-1321.

Usleber E., Dietrich E., Märtlbauer E. & Terplan G. (1994): Effect of heterologous paralytic shellfish poisoning toxin-enzyme conjugates on the cross-reactivity of a saxitoxin enzyme immunoassay. Letters in Applied Microbiology 18: 337-339.

Usleber E., Schneider E. & Terplan G. (1991): Direct enzyme immunoassay in microtitration plate and test strip format for the detection of saxitoxin in shellfish. Letters in Applied Microbiology 13: 275-277.

Utkilen H. & Gjølme N. (1992): Toxin production by Microcystis aeruginosa as a function of light in continuous cultures and its ecological significance. Applied and Environmental Microbiology 58: 1321-1325.

van der Westhuizen A.J. & Eloff J.N. (1983): Effect of culture age and pH of culture medium on the growth and toxicity of the blue-green alga Microcystis aeruginosa. Z. Pflanzenphysiol. Bd. 110: 157-163.

van der Westhuizen A.J. & Eloff J.N. (1985): Effect of temperature and light on the toxicity and growth of the blue-green alga Microcystis aeruginosa (UV-006). Planta 163: 55-59.

Vasconcelos V.M., Evans W.R., Carmichael W.W. & Namikoshi M. (1993): Isolation of microcystin-LR from a Microcystis (cyano-bacteria) waterbloom collected in the drinking water reservoir for Porto, Portugal. J. Environ. Sci. Health. A28 (9): 2081-2094.

Vezie C., Brient L., Sivonen K., Bertru G., Lefeuvre J.-C. & Salkinoja-Salonen M. (1998): Variation of microcystin content of cyanobacterial blooms and isolated strains in Lake Grand-Lieu (France). Microbial Ecology 35: 126-135.

Volterra L., Bruno M., Gucci P.M.B. & Pierdominici E. (1992): Fast method for detecting toxic cyanophyte blooms. Environmental Toxicology and Water Quality: 7: 215-222.

Vuori E., Pelander A., Himberg K., Waris M. & Niinivaara K. (1997): Removal of nodularin from brackish water with reverse osmosis or vacuum distillation. Water Research 31: 2922-2924.

Ward C.J., Beattie K.A., Lee E.Y.C. & Codd G.A. (1997): Colorimetric protein phosphatase inhibition assay of laboratory strains and natural blooms of cyanobacteria: comparisons with high-performance liquid chromatographic analysis for microcystins. FEMS Microbiology Letters 153: 465-473.

Watanabe M.F., Harada K.I., Matsuura K., Watanabe Y. & Suzuki M. (1989a): Heptapeptide toxins contained in natural samples of Microcystis species. Toxicity Assessment 4: 487-497.

Watanabe M.F., Harada S., K.I., Matsuura K., Watanabe M. and Suzuki M. (1989b): Heptapeptide toxin production during the batch culture of two microcystis species (cyanobactera). Journal of Applied Phycology, 1: 161-165.

Watanabe M.F. & Oishi S. (1980): Toxicities of Microcystis aeruginosa collected from some lakes, reservoirs, ponds and moat in Tokyo and adjacent regions. Jap. J. Limnol. 41: 5-9.

Watanabe M.F. & Oishi S. (1985): Effects of environmental factors on toxicity of a cyano-bacterium (Microcystis aeruginosa) under culture conditions. Applied and Environmental Microbiology 49: 1342-1344.

Watanabe M.F., Oishi S., Harada K-I., Matsuura K., Kawai H. & Suzuki M. (1988): Toxins contained in Microcystis species of cyanobacteria (blue-green algae). Toxicon 26 (11): 1017-1025.

Watanabe M.F., Park H.-D. & Watanabe M. (1994): Compositions of Microcystis species and heptapeptide toxins. Verh. Internat. Verein. Limnol. 25: 2226-2229.

Watanabe M.F., Tsuji K., Watanabe Y., Harada K-I. & Suzuki M. (1992a): Release of heptapeptide toxin (microcystin) during the decomposition process of Microcystis aeruginosa. Natural Toxins 1: 48-53.

Watanabe M.F., Watanabe M., Kato T., Harada K-I. & Suzuki M. (1991): Composition of cyclic peptide toxins among strains of Microcystis aeruginosa (blue-green algae, cyanobacteria). Bot. Mag. Tokyo 104: 49-57.

Watanabe M.M., Kaya K. & Takamura N. (1992b): Fate of the toxic cyclic hepapeptides, the microcystins, from blooms of Micro-cystis (cyanobacteria) in a hypertrophic lake. J. Phycol. 28: 761-767.

Weckesser J., Drews G. & Mayer H. (1979): Lipopolysaccharides of photosynthetic prokaryotes. Ann. Rev. Microbiol. 33: 215-239.

Weckesser J. & Martin C. (1990): Toxine aus cyanobacterien im wasser: Microcystin und verwandte peptide. Forum Mikrobiologie 7-8: 364-369.

Wicks R.J. & Thiel P.G. (1990): Environmental factors affecting the production of peptide toxins in floating scums of the cyanobacterium Microcystis aeruginosa in a hypertrophic African reservoir. Environ. Sci. Technol. 24: 1413-1418.

Windolf, J., E. Jeppesen, M. Søndergaard, J.P. Jensen & L. Sortkjær (1993): Ferske vandområder - søer. Vandmiljøplanens Overvågningsprogram 1992. Faglig rapport fra DMU nr. 90. Danmarks Miljøundersøgelser. 130 pp.

Wirsing B., Hoffmann L., Heinze R., Klein D., Daloze D., Braekman J.-C. & Weckesser J. (1998): First report on the identification of microcystin in a water bloom collected in Belgium. Systematic and Applied Microbiology 21: 23-27.

Yin Q., Carmichael W.W. & Evans W.R. (1997): Factors influencing growth and toxin production by cultures of the freshwater cyanobacterium Lyngbya wollei Farlow ex Gomont. Journal of Applied Phycology 9: 55-63.

Yu S-Z. (1989): Drinking water and primary liver cancer. - I: Tang Z.Y., Wu M.C. & Xia S.S. (Eds.): Primary liver cancer. China Academic Publishers, Springer, Berlin Heidelberg New York, pp. 30-37.

Zhang Q-X., Carmichael W.W., Yu M-J. & Li S-H. (1991): Cyclic peptide hepatotoxins from freshwater cyanobacterial (blue-green algae) waterblooms collected in Central China. Environmental Toxicology and Chemistry 10: 313-321.

Zilberg, B. (1966): Gastroentertitis in Salisbury European children- a five-year study. Cent. Afr. Journal medicine 12:164-168.

Århus Amt (1992a): Bryrup Langsø 1991. Miljøkontoret, Århus Amt, 44 pp.

Århus Amt (1992b): Ravn Sø 1991. Miljøkontoret, Århus Amt, 57 pp.

 

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