Report on the Health Effects of Selected Pesticide Coformulants

Table of Contents

Preface

Sammenfatning

Summary

1 Introduction
   1.1 Aim of the project
   1.2 Background
   1.3 Definitions
   1.4 Scope
   1.5 Existing regulation
      1.5.1 Approval procedure
      1.5.2 Classification and labelling
      1.5.3 Safety data sheets
   1.6 Lack of data
   1.7 Related projects
      1.7.1 Pilot project on coformulants in herbicides
      1.7.2 Nordic project on coformulants in plant protection products

2 Methodology
   2.1 Prioritisation of substances for the project
   2.2 Literature search
   2.3 Principles for the hazard assessment

3 Results
   3.1 Toxicological effects and data availability
   3.2 Short reports
      3.2.1 Manganese sulphate and manganese sulphide (Appendix 1)
      3.2.2 Diammonium sulphate (Appendix 2)
      3.2.3 Dimethyl ether (DME) (Appendix 3)
      3.2.4 Hexamethylenetetramine (Appendix 4)
      3.2.5  1-Methyl-1,2-ethanediyl dioleate (Appendix 5)
      3.2.6 Isopropyl myristate (Appendix 6)
      3.2.7 Sodium ligninsulphonate (Appendix 7)
      3.2.8 Calciumdodecylbenzenesulphonate (CaDBS) (Appendix 8)
      3.2.9 Ethylene Glycol (EG) (Appendix 9)
      3.2.10 Propylene Glycol (PG) (Appendix 10)
      3.2.11  2-Butoxyethanol (EGBE) (Appendix 11)
      3.2.12  1-Methoxy-2-propanol (2PG1ME) (Appendix 12)
      3.2.13 Diethylene glycol mono-n-butyl ether (DEGBE) (Appendix 13)
      3.2.14 Dipropylene glycol monomethyl ether (DPGME) (Appendix 14)
      3.2.15 Polyethylene glycol dodecyl ether (polyEGDE) (Appendix 15)
      3.2.16 Cyclohexanone (Appendix 16)
      3.2.17   1-Methylpyrrolidone (NMP) (Appendix 17)
      3.2.18   4- Hydroxy-4-methyl-2-pentanone (HMP) (Appendix 18)
   3.3 Critical effects and existing regulation

4 Discussion
   4.1 Data availability on the selected coformulants
   4.2 Toxicological effects of the selected coformulants
   4.3 Present regulation
   4.4 Limitation of the project

5 Conclusions
   5.1 Data availability on the selected coformulants
   5.2 Toxicological effects of the selected coformulants
   5.3 Limitation of the project

6 Recommendations

7 References