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Effects of azole fungicides on the function of sex and thyroid hormones
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Cholesterol
Mean (mM) |
Triglyceride
Mean (mM) |
T3
Mean (nM) |
T4
Mean (nM) |
Testosterone
Mean (nM) |
Progesterone
Mean (nM) |
| Control |
1.85±0.28(6) |
7.44±2.26(6) |
2.38±0.48(7) |
53.53±17.45(7) |
0.40±0.25(6) |
48±32(6) |
| Tebuconazole 50 mg/kg |
1.68±0.22(7) |
4.01±0.94(7) |
2.36±0.24(7) |
53.14±11.95(7) |
0.22±0.09(7) |
113±114(7) |
| Tebuconazole 100 mg/kg |
2.20±0.30(8) |
6.23±1.71(8) |
1.99±0.23* (8) |
38.26±10.74(8) |
0.32±0.17(8) |
354±163*(8) |
| Epoxiconazole 15 mg/kg |
1.90±0.31(8) |
6.14±3.92(8) |
2.47±0.25(8) |
46.44±9.05(8) |
0.49±0.31(9) |
170±141(9) |
| Epoxiconazole 50 mg/kg |
2.31±0.74(14) |
12.07±7.45(14) |
2.29±0.23(14) |
44.09±13.92(14) |
0.82±0.43* (15) |
349±190* 14) |
Data represent the mean±SD; ( ) = n; * statistically significantly different compared to control (P<0.05).
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Version 1.0 October 2007, © Danish Environmental Protection Agency
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