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Survey and Health Assement of the exposue of 2-year-olds to chemical substances in Consumer Product

Table 7.73 Daily uptake of parabens from cosmetic products on the basis of the maximum allowed concentrations in the products – more realistic values

Product Substance Amount of product (mg) Weight fraction of parabens in product. Retention factor F abs Number of uses per day Average weight, 2-year-old Daily uptake
(µg/kg BW/day)		 Calculated DNEL
(mg/kg BW/day)		 RCR
Creams Propylparaben 2700 0.004 1 0.1 3/7 15.2 30.5 0.03 1.0
  Butylparaben 2700 0.004 1 0.1 3/7 15.2 30.5 0.03 1.0
Sunscreens 7 days: Full body Propylparaben 18000 0.004 1 0.1 2 x 7/365* 15.2 18.2 0.03 0.6
Sunscreens 7 days: Full body Butylparaben 18000 0.004 1 0.1 2 x 7/365* 15.2 18.2 0.03 0.6
Sunscreens 14 days: Face, arms and legs Propylparaben 8600 0.004 1 0.1 2 x 14/365* 15.2 17.4 0.03 0.6
Sunscreens 14 days: Face, arms and legs Butylparaben 8600 0.004 1 0.1 2 x 14/365* 15.2 17.4 0.03 0.6
Sunscreens 11 days: Face and arms Propylparaben 3900 0.004 1 0.1 2 x 11/365* 15.2 6.2 0.03 0.2
Sunscreens 11 days: Face and arms Butylparaben 3900 0.004 1 0.1 2 x 11/365* 15.2 6.2 0.03 0.2
Sunscreens total Propylparaben             41.8   1.4
Sunscreens total Butylparaben             41.8   1.4
Shampoo Propylparaben 6000 0.004 0.01 0.1 3/7 15.2 0.7 0.03 0.02
  Butylparaben 6000 0.004 0.01 0.1 3/7 15.2 0.7 0.03 0.02
Liquid soap Propylparaben 2500 0.004 0.01 0.1 3/7 15.2 0.3 0.03 0.01
  Butylparaben 2500 0.004 0.01 0.1 3/7 15.2 0.3 0.03 0.01
Total Propylparaben             73.3   2.4
Total Butylparaben             73.3   2.4

* Sunscreens are only used in the summer period, hence a daily average use for the entire year has been calculated.

 

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Version 1.0 November 2009, © Danish Environmental Protection Agency