Mesocosm experiments in the approval procedure for pesticides

Contents

Foreword
 
Summary and conclusions
 
1 Objective
 
2 Introduction
 
3 Methods
 
4 Database/mesocosm data
 
5 PLS (partial least squares)
5.1 Development of PLS models
5.2 Interpretation of PLS models
5.3 Using the PLS models in a standardised evaluation procedure of pesticides
5.4 PLS models for macroinvertebrates
5.4.1 Interpretation of the PLS model for macroinvertebrates
5.4.2 Predicting effect concentrations for the macroinvertebrates with the aid of the PLS models
5.5 PLS models for zooplankton
5.5.1 Interpretation of the PLS model for zooplankton.
5.5.2 Predicting the effect concentrations for the zooplankton with the aid of the PLS model
5.6 PLS models for microalgae
5.6.1 Interpretation of the PLS model for microalgae
5.6.2 Predicting the effect concentrations for the micro algae with the aid of the PLS model
5.7 Summary of PLS models
 
6 Effect of pesticides in mesocosms
6.1 Phytoplankton and microalgae
6.2 Zooplankton
6.2.1 Statistical power of impact of insecticides on zooplankton in mesocosm experiments
6.2.2 Recovery of zooplankton populations
6.3 Indirect effects of insecticides on plankton.
6.4 Effect of Insecticides on Macroinvertebrates
6.4.1 Statistical power of impact of insecticides on macroinvertebrates in mesocosm experiments
6.4.2 Recovery of macroinvertebrates after insecticide exposure.
 
7 Comparison of extrapolated hazard concentration and observed effects in mesocosms
 
8 Conclusions and recommendations
 
9 Reference List
  
10 Annex
10.1 Annex A
10.2 Annex B
10.3 Annex C