Evaluation of in vitro assays for determination of estrogenic activity in the environment
TABLE 1. EEQ levels found in different environmental matrices in
various countries by use of in vitro assays
Matrix
EEQ
(ng/l)
Country
In vitro assay
Reference
Wastewater
influent
120
0.6-153
35-72
The Netherlands
The Netherlands
Japan
ER-CALUX
ER-CALUX
YES
Murk et al., 2002
Vethaak et al., 2002
Onda et al ., 2002
Wastewater
effluent
2-25
0.2-7.8
6
16
0.05-2.6
<d.l-4.46
£1-15
1.90-14.9
21-147
4-35
Germany
Germany
Germany
The Netherlands
The Netherlands
Belgium
USA
USA
USA
Japan
E-screen
E-screen
E-screen
ER-CALUX
ER-CALUX
YES
YES
MVLN
YES
YES
Körner et al ., 1999
Körner et al ., 2001
Körner et al ., 2000
Murk et al., 2002
Vethaak et al., 2002
Witters et al., 2001
Huggett et al ., 2003
Snyder et al., 2001
Tilton et al., 2002
Onda et al ., 2002
Surface
water
0.5
0.02-0.04
<d.l-81.4
<24
0.86-10.9
2.2-12.1
0.5-7.4
3.5
10
<d.l.-23.5
The Netherlands
The Netherlands
Belgium
United Kingdom
USA
China
Korea
Japan
Japan
South Africa
ER-CALUX
ER-CALUX
YES
YES
MVLN
MVLN, HGELN
E-screen
E-screen
YES
YES
Murk et al., 2002
Vethaak et al., 2002
Witters et al., 2001
Thomas et al., 2001
Snyder et al., 2001
Shen et al., 2001
Oh et al ., 2000
Behnish et al., 2001
Tashiro et al., 2003
Arijs et al., 2002
<d.l: below detection limit
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