Evaluation of Analytical Chemical Methods for Detection of Estrogens in the Environment
Advantages
Disadvantages
Sensitive
Not 100% specific, vulnerable to cross
reactivity
Rapid
Requires independent confirmation (e.g.
HPLC-MS-MS or GC-MS-MS)
Cost-effective
Not suitable for small sample loads
Small sample volume
Syntesis of antibody can be difficult and
expensive
Easy to use
Only one substance can be analysed at a
time
Wide applicability
Reduced sample preparation
Simultaneous analysis of multiple samples
Easily automated, ideal for large samples
load
Suited for field use
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