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Evaluation of Health Hazards by exposure to Triazines and Degradation Products

Contents

1 General description

• 1.1 Identity
• 1.2 Physical / chemical properties
• 1.3 Production and use
• 1.4 Environmental occurrence
  • 1.4.1 Air
  • 1.4.2 Water
  • 1.4.3 Soil
  • 1.4.4 Foodstuffs
• 1.5 Environmental fate
  • 1.5.1 Air
  • 1.5.2 Water
  • 1.5.3 Soil
  • 1.5.4 Bioaccumulation
• 1.6 Human exposure

2 Toxicokinetics

• 2.1 Absorption, distribution and excretion
  • 2.1.1 Inhalation
  • 2.1.2 Oral intake
  • 2.1.3 Dermal contact
• 2.2 Metabolism
• 2.3 Mode of action

3 Human toxicity

• 3.1 Single dose toxicity
• 3.2 Skin irritation
• 3.3 Sensitisation
• 3.4 Repeated dose toxicity
• 3.5 Toxicity to reproduction
• 3.6 Mutagenic and genotoxic effects
• 3.7 Carcinogenic effects

4 Animal toxicity

• 4.1 Single dose toxicity
  • 4.1.1 Inhalation
  • 4.1.2 Oral intake
  • 4.1.3 Dermal contact
• 4.2 Irritation
  • 4.2.1 Skin irritation
  • 4.2.2 Eye irritation
• 4.3 Sensitisation
• 4.4 Repeated dose toxicity
  • 4.4.1 Inhalation
  • 4.4.2 Oral intake
  • 4.4.3 Dermal contact
• 4.5 Toxicity to reproduction
  • 4.5.1 Inhalation
  • 4.5.2 Oral intake
  • 4.5.3 Dermal contact
  • 4.5.4 Other routes
• 4.6 Mutagenic and genotoxic effects
• 4.7 Carcinogenic effects

5 Regulations

• 5.1 Ambient air
• 5.2 Drinking water
• 5.3 Soil
• 5.4 Foods
• 5.5 Occupational Exposure Limits
• 5.6 Classification
• 5.7 IARC
• 5.8 US-EPA

6 Summary and evaluation

• 6.1 Description
• 6.2 Environment
• 6.3 Human exposure
• 6.4 Toxicokinetics
• 6.5 Mode of action
• 6.6 Human toxicity
  • 6.6.1 Single and repeated dose toxicity
  • 6.6.2 Skin irritation
  • 6.6.3 Sensitisation
  • 6.6.4 Toxicity to reproduction
  • 6.6.5 Mutagenic and genotoxic effects
  • 6.6.6 Carcinogenic effects
• 6.7 Animal toxicity
  • 6.7.1 Single dose toxicity
  • 6.7.2 Irritation
  • 6.7.3 Sensitisation
  • 6.7.4 Repeated dose toxicity
  • 6.7.5 Toxicity to reproduction
  • 6.7.6 Mutagenic and genotoxic effects
  • 6.7.7 Carcinogenic effects
• 6.8 Evaluation
  • 6.8.1 Critical effect(s) and NOAEL(s)

7 Risk characterisation via drinking water exposure

8 References

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Version 1.0 October 2004, © Danish Environmental Protection Agency