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Health effects assessment of exposure to particles from wood smoke

Contents

Preface

Summary

• Human exposure to particles from wood smoke
• Human health effects
  • Human non-cancer health effects from exposure to particles from wood smoke
  • Human carcinogenic effects from exposure to particles from wood smoke
• Data from studies in experimental animals
• Risk characterisation
• Recommendations

Sammenfatning

• Befolkningens udsættelse for partikler fra brænderøg
• Helbredseffekter, data fra befolkningsundersøgelser
  • Partikler generelt
  • Sundhedsskadelige effekter af partikler fra brænderøg
  • Kræftfremkaldende effekter af partikler fra brænderøg
• Viden fra undersøgelser med forsøgsdyr
• Risikokarakterisering
• Anbefalinger

1 Introduction

2 Wood smoke, characterisation

• 2.1 Particle size distribution
• 2.2 Chemical characterisation of wood smoke

3 Human exposure

• 3.1 Exposure from ambient air
  • 3.1.1 Particles
  • 3.1.2 PAH
• 3.2 Indoor penetration
• 3.3 Exposure from other settings with wood smoke
• 3.4 Summary of human exposure to particles from wood smoke

4 Toxicokinetics

• 4.1 Particle deposition in the respiratory tract
• 4.2 Clearance and translocation

5 Human health effects

• 5.1 Epidemiological studies, non-cancer health effects
  • 5.1.1 Particles in the general environment
  • 5.1.2 Particles from residential wood burning
  • 5.1.3 Other settings with wood smoke exposure
  • 5.1.4 Summary, non-cancer health effects
• 5.2 Epidemiological studies, carcinogenic effects
  • 5.2.1 Particles in the general environment
  • 5.2.2 Particles from wood burning
  • 5.2.3 Summary, carcinogenic effects

6 Experimental studies

• 6.1 Human studies
• 6.2 Studies in experimental animals
  • 6.2.1 Particles in the general environment, an overview
  • 6.2.2 Particles from wood smoke
• 6.3 In vitro studies
• 6.4 Summary, experimental studies

7 Risk assessment, wood smoke particles

• 7.1 Exposure assessment
• 7.2 Hazard assessment
  • 7.2.1 Hazard identification
  • 7.2.2 Hazard characterisation / dose-response relationship
• 7.3 Risk characterisation
  • 7.3.1 Estimated wood smoke PM exposure for risk characterisation
  • 7.3.2 Dose-response relationships for risk characterisation

8 Conclusions

• 8.1 Exposure assessment, wood smoke PM
• 8.2 Hazard assessment, wood smoke PM
• 8.3 Risk characterisation, wood smoke PM

9 Gaps of knowledge

• 9.1 Characterisation of wood smoke particles
• 9.2 Exposure assessment
• 9.3 Hazard assessment / risk characterisation
• 9.4 Mode of action
• 9.5 Recommendations

10 References

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Version 1.0 May 2008, © Danish Environmental Protection Agency