Name of colorant

Degree of evidence

References

Acid Orange 10

Negative results in ferrets for 12 months and mice lifelong

Burg and Charest, 1980

Acid Orange 20

Negative results in mice lifelong and rats for 2 years

Burg and Charest, 1980

Acid Red 14

Negative results in mice and rats for 12 months

Burg and Charest, 1980

Acid Red 27

Negative results in rats for 64-78 weeks, and in mice lifelong

Burg and Charest, 1980

Food Black 1

Negative results in mice for 80 weeks, and in rats for 2 years

Burg and Charest, 1980

Food Brown 3

Negative results in mice for 80 weeks, and in rats for 2 years

Burg and Charest, 1980

Food Red 1

No tumors induced in mice, rats nor dogs.

Longstaff, 1983

Food Yellow 3

Negative results in mice for 52 and 80 weeks, and in rats for, 64 weeks

Burg and Charest, 1980

Pigment Yellow 12 (pure)

No tumors induced in rats and mice tested for two years with 100 animals used per test group.

Longstaff, 1983, Burg and Charest, 1980

Pigment Yellow 16 (pure)

No tumors induced in rats and mice tested for two years with 100 animals used per test group.

Longstaff, 1983

Pigment Yellow 83 (pure)

No tumors induced in rats and mice tested for two years with 100 animals used per test group.

Longstaff, 1983

Solvent Orange 7

Negative results in rats for 65 weeks, and in mice for 52 weeks subcutaneous and oral

Burg and Charest, 1980

Solvent Yellow 5

No tumors induced in mice, rats, hamsters nor dogs.

Longstaff, 1983, Burg and Charest, 1980

Solvent YeIlow 6

Negative results in rats for 65 weeks - 2 years, and in dogs for 1 year

Burg and Charest, 1980