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Appendices 1-18 to: Report on the Health Effects of Selected Pesticide Coformulants

28   Regulations

28.1   Ambient air

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28.2   Drinking water

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28.3   Food

JECFA has set an ADI (acceptable daily intake) of 0-0.15 mg/kg b.w. for hexamethylenetetramine (JECFA 1974).

Hexamethylenetetramine may be used as a preservative (E239) in Provolone cheese in some countries.
However, on the Danish market it may not be used as a food additive  (Positivlisten 2000).

28.4   Cosmetics

Hexamethylenetetramine may legally be used as a preservative in cosmetic products in Europe at a maximum concentration of 0.15%. It may also be used in other concentrations for other purposes in cosmetics. (MM 2000).

28.5   Drugs

Hexamethylenetetramine may be used as a drug for urinary infections (Lægemiddelkataloget 2001).

28.6   Soil

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28.7   Occupational Exposure Limits

The occupational exposure limits in Norway, Sweden and Poland varies between 3 and 5 mg/m³ (RTECS 2000).

28.8   Classification

Hexamethylenetetramine is classified for flammability (F;R11 – highly flammable) and for sensitising properties (R42/43 – may cause sensitisation by inhalation and skin contact). (MM 2002).

28.9   IARC

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28.10   US-EPA

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