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Siloxanes - Consumption, Toxicity and Alternatives
Annex 7
Database screening for decamethyl cyclopentasiloxane
| Decamethyl cyclopentasiloxane |
CAS number: 541-02-6
Data compilation, environmental and health screening |
Summary |
Health and Environment:
No relevant information on health was found.
The substance decamethyl cyclopentasiloxane is only slightly soluble in water and has a high affinity for organic phases
(log Pow 5.2). Based on the physical/chemical properties Decamethyl cyclopentasiloxane is estimated to bioaccumulate,
and biodegradation is not expected. Data on environmental toxicity were not found. |
Identification of the substance
|
| CAS No. |
541-02-6 (CambridgeSoft Corp 2003) |
| EINECS |
No. 208-764-9 (Spin2000.net 2003) |
| EINECS Name |
Decamethylcyclopentasiloxane (HSDB 2003) |
| Synonyms |
Dimethylsiloxane pentamer (HSDB 2003), Cyclopentasiloxane, decamethyl-
(Spin2000.net 2003) |
| Molecular Formula |
C10-H30-O5-Si5 (HSDB 2003) |
| Structural Formula |
|
| Known Uses |
Paint, laquers and varnishing. Fuel additives. Surface treatment (Spin2000.net
2003) |
| IUCLID |
No data found |
| EU |
|
Physico-chemical Characteristics
|
| Physical Form |
Oily Liquid (HSDB 2003) |
| Molecular Weight (g/mole) |
378.80 (HSDB 2003) |
| Melting Point/range (°C) |
- 38°C (HSDB 2003) |
| Boiling Point/range (°C) |
210°C (HSDB 2003) |
| Decomposition Temperature (°C) |
No relevant data found |
| Vapour Pressure (mm Hg at °C) |
0.2 mm Hg at 25°C (HSDB 2003) |
| Density |
0.9593 at 20°C (HSDB 2003) |
| Vapour Density (air=1) |
No relevant data found |
| Solubility (water) |
0.017 mg/l at 25°C (PhysProp 2003) |
| Partition Coefficient (log Pow): |
5.20 (HSDB 2003) |
| pKa |
No relevant data found |
| Flammability |
Flashpoint 77°C (CambridgeSoft 2003) |
| Explosivity |
No relevant data found |
| Oxidising Properties |
No relevant data found |
Toxicological Data
|
| Observation in Humans |
None Found |
Acute Toxicity
|
| Oral |
No relevant data found |
| Dermal |
No relevant data found |
| Inhalation |
No relevant data found |
| Other Routes |
No relevant data found |
| Skin Irritation |
No relevant data found |
| Eye Irritation |
No relevant data found |
| Irritation of Respiratory Tract |
No relevant data found |
| Skin Sensitization |
No relevant data found |
| Sensitization by Inhalation |
No relevant data found |
Subchronic and Chronic Toxicity
|
| Observation in humans |
No relevant data found |
| Oral |
No relevant data found |
| Inhalation |
No relevant data found |
| Dermal |
No relevant data found |
Genotoxicity and Carcinogenicity
|
| Mutagenicity |
No relevant data found |
| Gene Mutation |
No relevant data found |
| Chromosome Abnormalities |
No relevant data found |
| Other Genotoxic Effects |
No relevant data found |
| Cancer Review |
No relevant data found |
Reproductive Toxicity, Embryotoxicity and Teratogenicity
|
| Reproductive Toxicity |
No relevant data found |
| Teratogenicity |
No relevant data found |
| Other Toxicity Studies |
No relevant data found |
| Toxicokinetics |
No relevant data found |
Ecotoxicity Data
|
| Algae |
No relevant data found |
| Crustacean |
No relevant data found |
| Fish |
No relevant data found |
| Bacteria |
No relevant data found |
Environmental Fate
|
| BCF |
Estimated 5300 (HSDB 2003) |
| Aerobic biodegradation |
Expected to be persistent (HSDB 2003) |
| Anaerobic biodegradation |
Expected to be persistent (HSDB 2003) |
| Metabolic pathway |
No relevant data found |
| Mobility |
Estimated immobile (HSDB 2003) |
Conclusion
|
| Health and Environment |
No relevant information on health was found and no conclusion can be drawn.
Based on the physical/chemical properties Decamethyl cyclopentasiloxane is estimated to bioaccumulate and biodegradation is not expected. Data on environmental toxicity were not found.
The substance has to be further investigated e.g. on substance group level before a conclusion can be made. |
List of references:
CambridgeSoft 2003. CambridgeSoft Corporation database (available at www.chemfinder.com)
HSDB 2003. HSDB database (available through toxnet.nlm.nih.gov)
PhysProp 2003. PHYSPROP DEMO-database (available at esc.syrres.com/interkow/physdemo)
Spin2000.net 2003. SPIN database (available at www.spin2000.net)
References used for screening:
- 1. Aquire (available at www.epa.gov/ecotox)
- 2. CambridgeSoft Corporation database (available at www.chemfinder.com)
- 3. HSDB database (available through toxnet.nlm.nih.gov)
- 4. IUCLID-CD (1996)
- 5. PHYSPROP DEMO-database (available at esc.syrres.com/interkow/physdemo)
- 6. SPIN database (available at www.spin2000.net)
- 7. DART Special (RTECS) (available through toxnet.nlm.nih.gov)
- 8. ToxLine (available through toxnet.nlm.nih.gov)
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Version 1.0 September 2005, © Danish Environmental Protection Agency
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