Mesocosm experiments in the approval procedure for pesticides, Danish Environmental Protection Agency

Mesocosm experiments in the approval procedure for pesticides

Comparison of extrapolated hazard concentrations and the lowest observed effect concentrations in the mesocosm experiments. HC_5,50: extrapolated hazard concentration. OECD₁₀: Hazard concentration according to OECD approach. NOEC: Yes = lowest test concentration were lower than the lowest effect concentration observed; No = effect was observed at the lowest test concentration applied. HC_5,50/LOEC = ratio between extrapolated hazard concentration (see Table 1) and lowest observed effect concentration. OECD/LOEC = ratio between hazard concentration (OECD₁₀ approach) and lowest observed effect concentration. HC_5,50/low = ratio between hazard concentration and the lowest test concentration applied. OECD/low = ratio between extrapolated hazard concentration (OECD₁₀ approach) and the lowest test concentration applied. Observed effects at lowest concentration: ß decrease (mostly in abundance); İ increase.

Exp code	Pesticide	Trivial name	HC_50,5	OECD ¹⁰	NOEC	HC_50,5 /LOEC	OECD/ LOEC	HC_50,5/ low	OECD/ low	Lowest observed effect
76tll	Insecticide	Lambda-cyhalothrin	0.08	0.01	Yes	80	10	800	100	ß Ephemeroptera
96mli	Insecticide	Fenvalerate	0.05	0.01	No	50	10	50	10	ß Tricopoptera emergence
57flm	Insecticide	Esfenvalerate	0.18	0.02	No	18	2	18	2	ß Chironomidae
44tll	Herbicide	2,4 D	1200	240	Yes	12	2.4	120	24	ß macrophyte biomass
113tll	Insecticide	Esfenvalerate	0.18	0.02	No	5.14	0.571	5.14	0.571	ß macroinvertebrates - İ phytoplankton
60flm	Insecticide	Lambda-cyhalothrin	0.08	0.01	No	4.71	0.588	4.71	0.588	ß Amfipoda
123flm	Insecticide	Lambda-cyhalothrin	0.08	0.01	No	4.71	0.588	4.71	0.588	ß macroinvertebrate groups
102tll	Insecticide	Lindan	2.93	1.8	Yes	3.66	2.25	2.93	1.8	ß Chironomid emergence
104tll	Insecticide	Lindan	2.93	1.8	Yes	3.26	2.00	2.93	1.8	ß Chaoborus mortality
77mli	Insecticide	Lindan	2.93	1.8	Yes	2.93	1.80	11.72	7.2	İ drift in Ephemeroptera
86mli	Insecticide	Fenvalerate	0.05	0.01	Yes	1.67	0.333	5	1	ß macroinvertebrate abundance
117tll	Herbicide	Atrazin	19.9	2.6	No	1.33	0.173	1.33	0.173	ß Phytoplankton decrease & İ rotifer (ind.eff)
82mli	Herbicide	Atrazin	19.9	2.6	No	1.22	0.160	1.22	0.160	ß Periphyte biovolume
118tll	Insecticide	Bifenthrin	0.04	0.01	No	1.03	0.256	1.03	0.256	ß Zooplankton
59flm	Insecticide	Esfenvalerate	0.18	0.02	Yes	1	0.111	18	2.000	ß copepod nauplii
33tll	Insecticide	Fenvalerate	0.05	0.01	Yes	1	0.200	5	1.000	ß crustacean zooplankton-İ rotifers
62flm	Herbicide	Atrazin	19.9	2.6	No	0.99	0.130	0.99	0.130	ß macrophyte coverage & ß insect emergence (ind.eff)
114tll	Herbicide	Atrazin	19.9	2.6	No	0.99	0.130	0.99	0.130	ß macrophyte coverage
78&79mli	Herbicide	Atrazin	19.9	2.6	No	0.83	0.108	0.83	0.108	ß periphyte chlorophyll
85tll	Insecticide	Permethrin	0.39	0.03	No	0.78	0.060	0.78	0.060	ß Cladocera-increase in rotifers
76mli	Insecticide	Lindan	2.93	1.8	No	0.73	0.450	0.73	0.450	İ drift in Ephemeroptera
87mli	Herbicide	Alachlor	0.73	0.6	No	0.73	0.600	0.73	0.600	ß periphyte abundance
47flm	Insecticide	Esfenvalerate	0.18	0.02	No	0.72	0.080	0.72	0.080	ß macroinvertebrate and zooplankton
49flm	Insecticide	Tebufenozide	87.3	16	Yes	0.67	0.123	1.25	0.229	ß Cladocera
111tll	Insecticide	Permethrin	0.39	0.03	No	0.52	0.040	0.52	0.040	ß Cladocera&Chaoborus
56flm	Insecticide	Chlorpyrifos	0.04	0.01	No	0.40	0.100	0.40	0.100	ß Amfipods & İ fil. algae
91mli	Insecticide	Chlorpyrifos	0.04	0.01	No	0.40	0.100	0.40	0.100	ß most insect larvae
55flm	Herbicide	Linuron	19.67	5.0	Yes	0.39	0.100	39.34	10.000	ß İ zooplankton
102mli	Insecticide	Permethrin	0.39	0.03	No	0.39	0.030	0.390	0.030	İ drift in Ephemeroptera
120tll	Insecticide	Bifenthrin	0.04	0.01	No	0.32	0.080	0.320	0.080	ß zooplankton
16ank	Herbicide	Atrazin	19.9	2.6	Yes	0.29	0.038	3.980	0.520	ß Copepod nauplii (ind.eff)
95mli	Insecticide	Fenitrothion	2.26	0.32	Yes	0.28	0.040	0.565	0.080	D Tricop. Behaviour
83tll	Insecticide	Cyfluthrin	0.07	0.01	No	0.28	0.040	0.280	0.040	ß most insect larvae
84tll	Insecticide	Cyfluthrin	0.07	0.01	No	0.28	0.040	0.280	0.040	ß most insect larvae
112tll	Insecticide	Permethrin	0.39	0.03	No	0.26	0.020	0.260	0.020	ß Cladocera & Chaoborus
72tll	Herbicide	Atrazin	19.9	2.6	No	0.25	0.033	0.249	0.033	ß periphyte abundance
38ank	Insecticide	Lindan	2.93	1.8	Yes	0.23	0.138	0.977	0.600	ß copepod nauplii
61flm	Herbicide	Atrazin	19.9	2.6	No	0.2	0.026	0.199	0.026	ß periphyte abundance & composition
109tll	Insecticide	Esfenvalerate	0.18	0.02	Yes	0.18	0.020	18.000	2.000	ß İ zooplankton
75tll	Insecticide	Carbaryl	0.58	0.07	Yes	0.12	0.014	0.290	0.035	ß Cladocera
28tll	Insecticide	Chlorpyrifos	0.04	0.01	No	0.08	0.020	0.080	0.020	ß zooplankton
90tll	Insecticide	Diflubenzuron	0.15	0.18	Yes	0.06	0.072	0.214	0.257	ß Diptera
119tll	Herbicide	Atrazin	19.9	2.6	No	0.05	0.007	0.052	0.007	ß phyto- and zooplankton
74mli	Herbicide	Triclopyr ester	131.12	120	Yes	0.04	0.038	0.410	0.375	İ drift in Tricoptera
124flm	Insecticide	Azinphos-methyl	0.05	0.02	Yes	0.02	0.009	2.000	0.800	İ Cyclopoida
26tll	Insecticide	Diflubenzuron	0.15	0.18	No	0.02	0.018	0.015	0.018	ß zooplankton; İ phytoplankton
27tll	Insecticide	Diflubenzuron	0.15	0.18	No	0.0	0.018	0.015	0.018	ß zooplankton; İ phytoplankton
61tll	Herbicide	Atrazin	19.9	2.6	Yes	0.01	0.002	0.166	0.022	ß periphyte abundance & composition
92mli	Insecticide	Chlorpyrifos	0.04	0.01	Yes	0.01	0.003	0.667	0.167	ß İ macroinvertebrates
54flm	Insecticide	Azinphos-methyl	0.05	0.02	Yes	0.01	0.005	0.250	0.100	ß Cladocera
64flm	Insecticide	Lindan	2.93	1.8	No	0.01	0.006	0.009	0.006	ß zooplankton; İ phytoplankton
46flm	Insecticide	Methoxychlor	0.09	0.08	Yes	0.01	0.007	0.009	0.008	ß crustacean zooplankton; İ rotifers
50flm	Insecticide	Chlorpyrifos	0.04	0.01	No	0.01	0.002	0.008	0.002	ß Amfipod & Isopod
57tll	Insecticide	Diazinone	0.03	0.003	Yes	0.01	0.000	0.013	0.000	ß Cladocera
125flm	Insecticide	Trahalomethrin	0.07	0.01	No	0.01	0.001	0.006	0.001	ß Ephemeroptera
58flm	Insecticide	Diflubenzuron	0.15	0.18	No	0.01	0.006	0.005	0.006	ß macroinvertebrate & zooplankton; İ phytoplankton
45flm	Insecticide	Methoxychlor	0.09	0.08	Yes	0.01	0.004	0.005	0.004	ß crustacean zooplankton; İ rotifers
110tll	Insecticide	Carbofuran	0.05	0.02	Yes	0.00	0.001	0.010	0.004	ß Diptera & Amfipoda
25tll	Insecticide	Endosulfan	0.02	0.01	Yes	0.00	0.001	0.020	0.010	ß Ostracoda; İ phytoplankton
44flm	Insecticide	Methoxychlor	0.09	0.08	Yes	0.00	0.002	0.018	0.016	ß crustacean zooplankton; İ rotifers
51flm	Insecticide	Chlorpyrifos	0.04	0.01	No	0.00	0.000	0.001	0.000	ß Amfipod & Isopod
53flm	Insecticide	Chlorpyrifos	0.04	0.01	No	0.00	0.000	0.001	0.000	ß most groups
101mli	Herbicide	Triclopyr ester	131.1	120	Yes	0.00	0.000	0.041	0.038	İ Drift & mortality in macroinvertebrates
43flm	Insecticide	Methoxychlor	0.09	0.08	Yes	0.00	0.000	0.030	0.027	ß zooplankton
63flm	Insecticide	Delta-methrin	0.01	0.003	No	0.00	0.000	0.000	0.000	ß zooplankton; İ phytoplankton